Skip to main content
SpringerLink
Log in

Lung Volume Reduction Surgery in the Candidate for Lung Transplantation

  • Chapter
Difficult Decisions in Thoracic Surgery

  • 1008 Accesses

Abstract

Emphysema is a progressive, unrelenting disease that results in a continued decline in pulmonary function. When pulmonary function testing documents a forced expiratory volume in 1s (FEV1) of less than 30% predicted values, the 3-year mortality risk has been estimated at 40% to 50%. Because of the increased mortality and the decreased quality of life seen with severe emphysema, multiple surgical treatments have been devised for patients with emphysema. The majority of these surgical interventions have been subsequently abandoned because of the lack of reproducible benefits and the false physiological principles upon which they were based. An excellent published review on the history of emphysema surgery has been provided by Deslauriers. As surgeons and physicians gained a better understanding of the pathophysiology of emphysema, most of these procedures would be considered of historical interest with no current practical value.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Diener CF, Burrows B. Further observations on the course and prognosis of chronic obstructive pulmonary disease. Am Rev Respir Dis 1975;111:719–724.

    PubMed  CAS  Google Scholar 

  2. Traver GA, Cline MG, Burrows B. Predictors of mortality in chronic obstructive pulmonary disease. Am Rev Respir Dis 1979;119:895–902.

    PubMed  CAS  Google Scholar 

  3. Burrows B, Earle RH. Course and prognosis of chronic obstructive lung disease: a prospective study of 200 patients. N Engl J Med 1969;280:397–404.

    Article  PubMed  CAS  Google Scholar 

  4. Nocturnal-Oxygen-Therapy-Trial-Group. Continuous or nocturnal oxygen therapy in hypoxemic chronic obstructive lung disease. Ann Intern Med 1980;93:391–398.

    Google Scholar 

  5. Deslauriers J. History of surgery for emphysema. Semin Thorac Cardiovasc Surg 1996;8:43–51.

    PubMed  CAS  Google Scholar 

  6. Mal H, Andreasian B, Pamela F. Unilateral lung transplantation in end stage pulmonary emphysema. Am Rev Respir Dis 1989;140:797–802.

    PubMed  CAS  Google Scholar 

  7. Patterson GA, Cooper JD, Goldman B, et al. Technique of successful clinical double-lung transplantation. Ann Thorac Surg 1988;45:626–633.

    Article  PubMed  CAS  Google Scholar 

  8. Pasque MK, Cooper JD, Kaiser LR, Haydock DA, Triantafillou A, Trulock EP. An improved technique for bilateral lung transplantation: rationale and initial clinical experience. Ann Thorac Surg 1990;49:785–791.

    Article  PubMed  CAS  Google Scholar 

  9. Trulock EP, Edwards LB, Taylor DO, Boucek MM, Keck BM, Hertz MI. The Registry of the International Society for Heart and Lung Transplantation: twenty-second official adult lung and heart-lung transplant report — 2005. J Heart Lung Transplant 2005;24:956–967.

    Article  PubMed  Google Scholar 

  10. Trulock EP. Lung transplantation. Am J Respir Crit Care Med 1997;155:789–818.

    PubMed  CAS  Google Scholar 

  11. Low DE, Trulock EP, Kaiser LR, et al. Morbidity, mortality, and early results of single versus bilateral lung transplantation for emphysema. J Thorac Cardiovasc Surg 1992;103:1119–1126.

    PubMed  CAS  Google Scholar 

  12. Patterson GA, Maurer JA, Williams TJ, et al. Comparison of outcomes of double and single lung transplantation for obstructive lung disease. J Thorac Cardiovasc Surg 1991;101:623–632.

    PubMed  CAS  Google Scholar 

  13. Cassivi SD, Meyers BF, Battafarano RJ, et al. Thriteen-year experience in lung transplantation for emphysema. Ann Thorac Surg 2002;74:1663–1670.

    Article  PubMed  Google Scholar 

  14. Hadjiliadis D, Davis RD, Palmer SM. Is transplant operation important in determining posttran-splant risk of bronchiolitis obliterans syndrome in lung transplant recipients? [see comment]. Chest 2002;122:1168–1175.

    Article  PubMed  Google Scholar 

  15. Gaissert HA, Trulock EP, Cooper JD, Sundaresan RS, Patterson GA. Comparison of early functional results after volume reduction or lung transplantation for chronic obstructive pulmonary disease. J Thorac Cardiovasc Surg 1996;111:296–307.

    Article  PubMed  CAS  Google Scholar 

  16. Fishman A, Martinez F, Naunheim K, et al. A randomized trial comparing lung-volume-reduction surgery with medical therapy for severe emphysema [comment]. N Engl J Med 2003;348:2059–2073.

    Article  PubMed  Google Scholar 

  17. Meyers BF, Yusen RD, Guthrie TJ, et al. Results of lung volume reduction surgery in patients meeting a national emphysema treatment trial high-risk criterion [see comment]. J Thorac Cardiovasc Surg 2004;127:829–835.

    Article  PubMed  Google Scholar 

  18. Cooper JD, Trulock EP, Triantafillou AN, et al. Bilateral pneumectomy (volume reduction) for chronic obstructive pulmonary disease. J Thorac Cardiovasc Surg 1995;109:106–116; discussion 16–19.

    Article  PubMed  CAS  Google Scholar 

  19. Cooper JD. Clinical trials and future prospects for lung volume reduction surgery. Semin Thorac Cardiovasc Surg 2002;14:365–370.

    Article  PubMed  Google Scholar 

  20. Sciurba FC, Rogers RM, Keenan RJ, et al. Improvement in pulmonary function and elastic recoil after lung-reduction surgery for diffuse emphysema [comment]. N Engl J Med 1996;334:1095–1099.

    Article  PubMed  CAS  Google Scholar 

  21. Meyers BF. Complications of lung volume reduction surgery. Semin Thorac Cardiovasc Surg 2002;14:399–402.

    Article  PubMed  Google Scholar 

  22. Geddes D, Davies M, Koyama H, et al. Effect of lung-volume-reduction surgery in patients with severe emphysema. N Engl J Med 2000;343:239–245.

    Article  PubMed  CAS  Google Scholar 

  23. Criner GJ, Cordova FC, Furukawa S, et al. Prospective randomized trial comparing bilateral lung volume reduction surgery to pulmonary rehabilitation in severe chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999;160:2018–2027.

    PubMed  CAS  Google Scholar 

  24. Pompeo E, Marino M, Nofroni I, Matteucci G, Mineo TC. Reduction pneumoplasty versus respiratory rehabilitation in severe emphysema: a randomized study. Pulmonary Emphysema Research Group. Ann Thorac Surg 2000;70:948–953; discussion 954.

    Article  PubMed  CAS  Google Scholar 

  25. Goodnight-White S, Jones WJ, Baaklini J, et al. Prospective randomized controlled trial comparing bilateral lung volume reduction surgery (LVRS) to medical therapy a lone in patients with severe emphysema. Chest 2000;118(suppl 4):102S.

    Google Scholar 

  26. Lofdahl CG, Hillerdal G, Strom K. Randomized controlled trial of volume reduction surgery-preliminary results up to12 months. Am J Respir Crit Care Med 2000;161:A585.

    Google Scholar 

  27. Anonymous. Rationale and design of the National Emphysema Treatment Trial (NETT): a prospective randomized trial of lung volume reduction surgery. J Thorac Cardiovasc Surg 1999;118:518–528.

    Google Scholar 

  28. National Emphysema Treatment Trial Research Group. Patients at high risk of death after lung-volume-reduction surgery [comment]. N Engl J Med 2001;345:1075–1083.

    Article  Google Scholar 

  29. Ware JH. The National Emphysema Treatment Trial — how strong is the evidence? [comment]. N Engl J Med 2003;348:2055–2056.

    Article  PubMed  Google Scholar 

  30. Todd TRJ, Perron J, Winton TL, Keshavjee SH. Simultaneous single-lung transplantation and lung volume reduction. Ann Thorac Surg 1997;63:1468–1470.

    Article  PubMed  CAS  Google Scholar 

  31. Yonan N A, El-Gamel A, Egan J, Kakadellis J, Rahman A, Deiraniya AK. Single lung transplantation for emphysema: predictors for native-lung hyperinflation. J Heart Lung Transplant 1998;17:192–201.

    PubMed  CAS  Google Scholar 

  32. Kroshus TJ, Bolman RM, Kshettry VR. Unilateral volume reduction after single-lung transplantation for emphysema. Ann Thorac Surg 1996;62:363–368.

    Article  PubMed  CAS  Google Scholar 

  33. Le Pimpec-Barthes F, Debrosse D, Cuenod C-A, Gandjbakhch I, Riquet M. Late contralateral lobectomy after single-lung transplantation for emphysema. Ann Thorac Surg 1996;61:231–234.

    Article  PubMed  Google Scholar 

  34. Zenati M, Keenan RJ, Landreneau RJ, Paradis IL, Ferson PF, Griffith BP. Lung reduction as a bridge to lung transplantation in pulmonary emphysema. Ann Thorac Surg 1995;59:1581–1583.

    Article  PubMed  CAS  Google Scholar 

  35. Bavaria JE, Pochettino A, Kotloff RM, et al. Effect of volume reduction on lung transplant timing and selection for chronic obstructive pulmonary disease. J Thorac Cardiovasc Surg 1998;115:9–18.

    Article  PubMed  CAS  Google Scholar 

  36. Meyers BF, Yusen RD, Guthrie TJ, et al. Outcome of bilateral lung volume reduction in patients with emphysema potentially eligible for lung transplantation. J Thorac Cardiovasc Surg 2001;122:10–17.

    Article  PubMed  CAS  Google Scholar 

  37. Ciccone AM, Meyers BF, Guthrie TJ, et al. Long-term outcome of bilateral lung volume reduction in 250 consecutive patients with emphysema [comment]. J Thorac Cardiovasc Surg 2003;125:513–525.

    Article  PubMed  Google Scholar 

  38. Senbaklavaci O, Wisser W, Ozpeker C, et al. Successful lung volume reduction surgery brings patients into better condition for later lung transplantation. Eur J Cardiothorac Surg 2002;22:363–367.

    Article  PubMed  Google Scholar 

  39. Burns KE, Keenan RJ, Grgurich WF, Manzetti JD, Zenati MA. Outcomes of lung volume reduction surgery followed by lung transplantation: a matched cohort study. Ann Thorac Surg 2002;73:1587–1593.

    Article  PubMed  Google Scholar 

  40. Lau CL, Guthrie TJ, Chaparro C, et al. Lung transplantation in recipients with previous lung volume reduction surgery. J Heart Lung Transplant 2003;22(suppl 1):S183.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Section of Thoracic Surgery, University of Michigan Medical Center, Ann Arbor, MI, USA

    Christine L. Lau MD

  2. Division of Cardiothoracic Surgery, Washington University School of Medicine, St. Louis, MO, USA

    Bryan F. Meyers MD, MPH

Authors
  1. Christine L. Lau MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Bryan F. Meyers MD, MPH
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Surgery, The University of Chicago, Chicago, IL, USA

    Mark K. Ferguson MD (Professor and Head) (Professor and Head)

  2. Thoracic Surgery Service, The University of Chicago Hospitals, Chicago, IL, USA

    Mark K. Ferguson MD (Professor and Head) (Professor and Head)

Rights and permissions

Reprints and permissions

Copyright information

© 2007 Springer-Verlag London Limited

About this chapter

Cite this chapter

Lau, C.L., Meyers, B.F. (2007). Lung Volume Reduction Surgery in the Candidate for Lung Transplantation. In: Ferguson, M.K. (eds) Difficult Decisions in Thoracic Surgery. Springer, London. https://doi.org/10.1007/978-1-84628-474-8_21

Download citation

  • DOI: https://doi.org/10.1007/978-1-84628-474-8_21

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84628-384-0

  • Online ISBN: 978-1-84628-474-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation