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First Clinical Data on Sildenafil: The Arrival of Oral Pharmacotherapy

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Key Clinical Trials in Erectile Dysfunction
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Abstract

This represented the first serious publication indicating the potential utility of sildenafil in the treatment of erectile dysfunction (ED). It represented the arrival of oral therapy for the treatment of ED, offering much hope to patients and physicians alike.

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11.1 Key Trial References

11.1.1 Major Publication

  • Boolell M, Allen M, et al. Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction. Int J Impot Res 8:47–52, 1996.

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11.1.2 Other Important Publications

  • Boolell M, Gepi-Attee S, et al. Sildenafil, a novel effective oral therapy for male erectile dysfunction. Br J Urol 78:257–261, 1996.

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  • Olsson A, Speakman M, et al. Sildenafil citrate (Viagra) is effective and well tolerated for treating erectile dysfunction of psychogenic or mixed aetiology. Int J Clin Pract 54(9):561–566, 2000.

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  • Eardley I, Morgan R, et al. Efficacy and safety of sildenafil citrate in the treatment of men with mild to moderate erectile dysfunction. Br J Psychiat 178:325–330, 2001.

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© 2007 Springer-Verlag London Limited

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(2007). First Clinical Data on Sildenafil: The Arrival of Oral Pharmacotherapy. In: Key Clinical Trials in Erectile Dysfunction. Springer, London. https://doi.org/10.1007/978-1-84628-428-1_11

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  • DOI: https://doi.org/10.1007/978-1-84628-428-1_11

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84628-427-4

  • Online ISBN: 978-1-84628-428-1

  • eBook Packages: MedicineMedicine (R0)

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