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Engineering Polymeric Scaffolds for Bone Grafts

  • Martha W. Betz
  • Diana M. Yoon
  • John P. Fisher
Chapter
Part of the Topics in Bone Biology book series (TBB, volume 3)

Abstract

Orthopedic injuries resulting from trauma or improper development often require surgical intervention to restore natural tissue function. Currently, over one million operations are performed annually for the surgical reconstruction of bone [50]. The well-known limitations associated with autografts, allografts, and bone cements have led to the investigation of synthetic polymers as support matrices for bone tissue engineering. Polymers are long-chain molecules that are formed by linking repetitive monomer units. They have been extensively studied for tissue-engineering applications. Constructs designed from these polymers can act as a support matrix to deliver cell populations or induce surrounding tissue ingrowth. The properties of scaffolds directly determine their success in tissue engineering and must be designed specifically for each application.

Keywords

Tissue Engineering Bone Tissue Engineering Porous Scaffold Fuse Deposition Modeling Biomed Mater 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag London Limited 2007

Authors and Affiliations

  • Martha W. Betz
    • 1
  • Diana M. Yoon
    • 2
  • John P. Fisher
    • 3
  1. 1.Bioengineering Graduate ProgramUniversity of MarylandCollege ParkUSA
  2. 2.Department of Chemical and Biomolecular EngineeringUniversity of MarylandCollege ParkUSA
  3. 3.Department of Chemical and Biomolecular Engineering and Bioengineering Graduate ProgramUniversity of MarylandCollege ParkUSA

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