Stem Cells and the Art of Mesenchymal Maintenance

  • Kevin C. Hicok
  • Marc H. Hedrick
Part of the Topics in Bone Biology book series (TBB, volume 3)


The most promising emergent medical technology of the early twenty-first century is stem-cell therapeutics. Traditionally, stem cells possess two important characteristics: the ability to undergo nearly unlimited self-renewal and the capability to differentiate into many (multipotent/pluripotent) or all (totipotent) mature cell phenotypes. The existence of stem cells and their ability to generate every tissue of the body during embryonic development has been known for many years. Transplant experiments performed in the 1970s, in which single stem cells were injected into early-stage blastulas, produced a chimera of donor and recipient cells in each organ of the resultant animal [29, 47].


Stem Cell Anterior Cruciate Ligament Mesenchymal Stem Cell Adult Stem Cell Somatic Cell Nuclear Transfer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag London Limited 2007

Authors and Affiliations

  • Kevin C. Hicok
    • 1
  • Marc H. Hedrick
    • 2
  1. 1.Biologics Research LaboratoriesCytori Therapeutics Inc.San DiegoUSA
  2. 2.Cytori Therapeutics Inc.San DiegoUSA

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