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Neurosurgical Management of High-grade Gliomas

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Book cover Tumor Neurosurgery

Part of the book series: Springer Specialist Surgery Series ((SPECIALIST))

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Abstract

High-grade gliomas include malignant variants of tumors derived from astrocytic and oligodendropheral cell lines. These tumors demonstrate invasive behavior, are rapidly growing and are usually characterized by contrast enhancement and edema on MR or CT neuroimaging. Management includes either biopsy or surgical resection followed by radiotherapy in the majority of cases. Additional adjuvant chemotherapy is also a treatment consideration. Despite advances in management, the prognosis remains poor, with few patients surviving beyond 2–3 years.

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Author information

Authors and Affiliations

  1. Department of Neurological Surgery, University of Washington Medical Center, Seattle, WA, USA

    Robert C. Rostomily MD, Alexander M. Spence MD & Daniel L. Silbergeld MD

Authors
  1. Robert C. Rostomily MD
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  2. Alexander M. Spence MD
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  3. Daniel L. Silbergeld MD
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Editor information

Editors and Affiliations

  1. South West Neurosurgery Centre, Derriford Hospital, Plymouth, UK

    Anne J. Moore MB BS, BSc, FRCS

  2. The Seattle Neuroscience Institute, Seattle, WA, USA

    David W. Newell

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© 2006 Springer-Verlag London Limited

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Rostomily, R.C., Spence, A.M., Silbergeld, D.L. (2006). Neurosurgical Management of High-grade Gliomas. In: Moore, A.J., Newell, D.W. (eds) Tumor Neurosurgery. Springer Specialist Surgery Series. Springer, London. https://doi.org/10.1007/978-1-84628-294-2_10

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  • DOI: https://doi.org/10.1007/978-1-84628-294-2_10

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84628-291-1

  • Online ISBN: 978-1-84628-294-2

  • eBook Packages: MedicineMedicine (R0)

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