Abstract
The incidence of obesity is rising dramatically all over the world leading to a further and enormous increase in obesity-related disorders such as atherosclerosis, type 2 diabetes (T2D), nonalcoholic fatty liver disease (NAFLD), and certain cancers. Obesity, in particular but not only visceral obesity, which is the accumulation of adipose tissue inside the abdominal cavity, is commonly associated with insulin resistance finally resulting in the development of T2D. Obesity and related insulin resistance are frequently correlated with a state of low-grade inflammation and therefore it is assumed that inflammation contributes to its development [25, 53]. Furthermore, although evidence is limited, obesity might be associated with some immune-mediated disorders such as asthma, psoriasis, and certain cancers.
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Wieser, V., Moschen, A.R., Tilg, H. (2014). Adipose Tissue Inflammation. In: Fantuzzi, G., Braunschweig, C. (eds) Adipose Tissue and Adipokines in Health and Disease. Nutrition and Health. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-770-9_7
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