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Exercise and the Hypothalamus. Ovulatory Adaptations

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Endocrinology of Physical Activity and Sport

Part of the book series: Contemporary Endocrinology ((COE))

Abstract

As early as 1939, Hans Selye, who later received the Nobel prize for work on the endocrinology of the adaptation response, reported that muscular exercise was often a cause for “menstrual irregularities” in women [1]. Selye performed controlled animal experiments showing that whether or not exercise suppresses reproduction depends on the abruptness of exercise onset [1]. Forty years later, Shangold et al. [2] published the first prospective observational study documenting gradual shortening of the luteal-phase length with increased running activity in one woman with regular menstrual cycles. Despite these early observations indicating that subtle alterations of ovulatory function occur within cycles of normal length, the exercise science literature has since focused on the absence (amenorrhea) or presence (eumenorrhea) of menstrual flow in women athletes. The purpose of this chapter is to review the subtle (and clinically important) ovulatory changes in response to exercise.

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Authors and Affiliations

  1. School of Human Kinetics, University of British Columbia, Vancouver, BC, Canada

    Moira A. Petit PHD

  2. Division of Endocrinology and Metabolism, Department of Medicine, University of British Columbia, Vancouver, BC, Canada

    Jerilynn C. Prior MD

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  1. Moira A. Petit PHD
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  1. , Department of Orthopedic Surgery, Hadassah-Hebrew UMC, 4 Ha'razim St, Jerusalem, 91120, Jerusalem, Israel

    Naama Constantini

  2. , Applied Physiology Laboratory, UNC at Chapel Hill, 203 Fezter Hall, Chapel Hill, 27599, North Carolina, USA

    Anthony C. Hackney

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Petit, M.A., Prior, J.C. (2013). Exercise and the Hypothalamus. Ovulatory Adaptations. In: Constantini, N., Hackney, A. (eds) Endocrinology of Physical Activity and Sport. Contemporary Endocrinology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-314-5_8

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