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Biomarkers of Neurological Disorders

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Applications of Biotechnology in Neurology

Abstract

A biomarker is a characteristic that can be objectively measured and evaluated as an indicator of a physiological as well as a pathological process or pharmacological response to a therapeutic intervention. Classical biomarkers are measurable alterations in blood pressure, blood lactate levels following exercise and blood glucose in diabetes mellitus. Any specific molecular alteration of a cell on DNA, RNA, metabolite or protein level can be referred to as a molecular biomarker. In the era of molecular biology, biomarkers usually mean molecular biomarkers and can be divided into three broad categories (Jain 2010):

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    Kewal K. Jain MD, FRACS, FFPM

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Jain, K.K. (2013). Biomarkers of Neurological Disorders. In: Applications of Biotechnology in Neurology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-272-8_4

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