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Nutritional Requirements and Support in Liver Disease

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Nutrition in Infancy

Part of the book series: Nutrition and Health ((NH))

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Abstract

The liver has a central role in energy metabolism, nutritional homeostasis and absorption of nutrients. Severe liver disease, whether acute or chronic, leads to multiorgan failure, which can have significant effects on growth and development in the long term. Malnutrition is common in infants and children with chronic liver disease (CLD). The pathophysiology of malnutrition in liver disease is complex and multifactorial and has extensive implications. Insufficient dietary intake is probably the most important factor and is correctable (Table 7.1). It is most severe in infants with chronic cholestatic liver disease, who are particularly vulnerable to the effects of malnutrition because of their high-energy and growth requirements [1].

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Authors and Affiliations

  1. The Liver Unit, The Department of Gastroenterology and Nutrition and Dietetic Department, Birmingham Children’s Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK

    Deirdre A. Kelly F.R.C.P.H., F.R.C.P., F.R.C.P.I., M.D., Susan Protheroe & Sara Clarke

Authors
  1. Deirdre A. Kelly F.R.C.P.H., F.R.C.P., F.R.C.P.I., M.D.
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  2. Susan Protheroe
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  3. Sara Clarke
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Corresponding author

Correspondence to Deirdre A. Kelly F.R.C.P.H., F.R.C.P., F.R.C.P.I., M.D. .

Editor information

Editors and Affiliations

  1. Arizona Health Science Center, Mel and Enid Zuckerman, University of Arizona, 1295 N. Martin, Tucson, 85724-5155, Arizona, USA

    Ronald Ross Watson

  2. Centre for Gastroenterology, and Nutrition, University College London, Gower Street, London, WC1E 6BT, United Kingdom

    George Grimble

  3. School of Medicine, Diabetes & Nutritional, King's College London, 150 Stamford St., London, SE1 9NH, United Kingdom

    Victor R. Preedy

  4. Division of Health Promotion Sciences, Mel and Enid Zuckerman, University of Arizona, 1295 N. Martin Avenue, Tucson, 85724, Arizona, USA

    Sherma Zibadi

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Kelly, D.A., Protheroe, S., Clarke, S. (2013). Nutritional Requirements and Support in Liver Disease. In: Watson, R., Grimble, G., Preedy, V., Zibadi, S. (eds) Nutrition in Infancy. Nutrition and Health. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-254-4_7

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  • DOI: https://doi.org/10.1007/978-1-62703-254-4_7

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-253-7

  • Online ISBN: 978-1-62703-254-4

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