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Biopsy Strategies to Detect Small Prostate Cancers

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Imaging and Focal Therapy of Early Prostate Cancer

Part of the book series: Current Clinical Urology ((CCU))

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Abstract

Early detection of prostate cancer with PSA screening and transrectal ultrasound-guided prostate biopsy has led to stage migration and decreased prostate cancer-related death. Early experience with laterally directed sextant prostate biopsy demonstrated good yield for early prostate cancer detection, but at a cost of missing some smaller cancers. Extended (12–14 cores) prostate biopsies enhanced this yield, and with the development of effective local prostatic nerve block techniques, office-based saturation biopsy techniques with 20 or more cores have become the gold standard for prostate cancer detection in patients with high risk features, although intriguing data on transperineal template-guided mapping biopsy are emerging. Improved detection of small cancers assists the patient and clinician in making treatment decisions, including the decision to embark on active surveillance of a small low grade prostate cancer. In the setting of detecting a small high grade cancer, early detection can potentially improve overall survival rates.

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Author information

Authors and Affiliations

  1. Department of Urology, Cleveland Clinic, 9500 Euclid Avenue Q10-1, Cleveland, OH, 44195, USA

    Ryan Berglund M.D.

  2. Department of Regional Urology, Glickman Urological and Kidney Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH, 44195, USA

    J. Stephen Jones M.D., F.A.C.S., M.B.A.

Authors
  1. Ryan Berglund M.D.
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  2. J. Stephen Jones M.D., F.A.C.S., M.B.A.
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Corresponding author

Correspondence to Ryan Berglund M.D. .

Editor information

Editors and Affiliations

  1. , Department of Surgery, Duke Cancer Institute, Room 1089 Duke South, Durham, 27710, North Carolina, USA

    Thomas J. Polascik

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Berglund, R., Jones, J.S. (2013). Biopsy Strategies to Detect Small Prostate Cancers. In: Polascik, T. (eds) Imaging and Focal Therapy of Early Prostate Cancer. Current Clinical Urology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-182-0_7

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  • DOI: https://doi.org/10.1007/978-1-62703-182-0_7

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-181-3

  • Online ISBN: 978-1-62703-182-0

  • eBook Packages: MedicineMedicine (R0)

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