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Standardisation of Focal Therapy Protocols

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Imaging and Focal Therapy of Early Prostate Cancer

Part of the book series: Current Clinical Urology ((CCU))

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Abstract

The concept of focal therapy, in its various modalities, is currently being explored within several clinical trials. All of these studies address the concept of targeting treatment only to the cancer, with sparing of normal tissue, in the aim of reducing treatment-related harm. However, the conduct of these trials varies significantly in terms of eligibility criteria, diagnostic investigations, treatment protocols, and follow-up strategies. This chapter explores the components of a focal therapy trial protocol and the possibilities for optimising and standardising its components in order to improve research outputs and comparison of results.

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Authors and Affiliations

  1. Department of Urology, University College Hospitals NHS Foundation Trust, 250 Euston Road, London, NW1 2PG, UK

    Louise Dickinson M.B.B.S., B.SC(Hons), M.R.C.S. & Hashim Uddin Ahmed M.R.C.S.(Ed), B.M., B.Ch(Oxon)

  2. Division of Surgical and Interventional Sciences and Department of Urology, University College London and University College Hospitals NHS Foundation Trust, 250 Euston Road, London, NW1 2PG, UK

    Mark Emberton M.D., F.R.C.S.(Uroi)

Authors
  1. Louise Dickinson M.B.B.S., B.SC(Hons), M.R.C.S.
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  2. Hashim Uddin Ahmed M.R.C.S.(Ed), B.M., B.Ch(Oxon)
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  3. Mark Emberton M.D., F.R.C.S.(Uroi)
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Corresponding author

Correspondence to Louise Dickinson M.B.B.S., B.SC(Hons), M.R.C.S. .

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Editors and Affiliations

  1. , Department of Surgery, Duke Cancer Institute, Room 1089 Duke South, Durham, 27710, North Carolina, USA

    Thomas J. Polascik

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Dickinson, L., Ahmed, H.U., Emberton, M. (2013). Standardisation of Focal Therapy Protocols. In: Polascik, T. (eds) Imaging and Focal Therapy of Early Prostate Cancer. Current Clinical Urology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-182-0_19

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  • DOI: https://doi.org/10.1007/978-1-62703-182-0_19

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-181-3

  • Online ISBN: 978-1-62703-182-0

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