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Cardiac Tumor Pathology pp 183–193Cite as

Novelties in Immunohistochemical and Molecular Study of Cardiac Tumors

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Part of the book series: Current Clinical Pathology ((CCPATH))

Abstract

Cardiac tumors are rare entities [1, 2]. Because of the rarity, it is difficult to investigate systematically large series of cardiac tumors using ancillary or biomolecular and experimental methods of investigation. As a consequence, scarce innovative information is available concerning the histogenesis of the majority of cardiac tumors. Myxomas are the most frequent neoplasms, accounting for 50 % of all tumors (Reynen K. N Engl J Med 333:1610–17, 1995; Burke AP, Virmani R. Atlas of tumor pathology, 3rd ed. Armed Forced Institute of Pathology: Washington, DC. p. 121–46, 1996), and the most investigated primary cardiac tumor. Nevertheless, the origin of myxoma remains uncertain. In this chapter, we summarize the most recent novelties in the biomolecular and immunohistochemical investigation of primary cardiac tumors.

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Authors and Affiliations

  1. Department of Biomedicine and Prevention, Institute of Anatomic Pathology, Tor Vergata University of Rome, Via Montpellier, Rome, 00133, Italy

    Augusto Orlandi M.D. & Luigi Giusto Spagnoli M.D.

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  1. Augusto Orlandi M.D.
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  2. Luigi Giusto Spagnoli M.D.
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Correspondence to Augusto Orlandi M.D. .

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Editors and Affiliations

  1. Thoracic and Vascular Sciences, Department of Cardiac, University of Padua, Padova, 35121, Italy

    Cristina Basso

  2. Thoracic and Vascular Sciences, Department of Cardiac,, University of Padua, Padova, 35121, Italy

    Marialuisa Valente

  3. Thoracic and Vascular Sciences, Department of Cardiac,, University of Padua, Padova, 35121, Italy

    Gaetano Thiene

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Orlandi, A., Spagnoli, L.G. (2013). Novelties in Immunohistochemical and Molecular Study of Cardiac Tumors. In: Basso, C., Valente, M., Thiene, G. (eds) Cardiac Tumor Pathology. Current Clinical Pathology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-143-1_13

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  • DOI: https://doi.org/10.1007/978-1-62703-143-1_13

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