Pediatric Bone Tumors

  • Roberto A. Leon-Ferre
  • Eduardo V. ZambranoEmail author
Part of the Molecular and Translational Medicine book series (MOLEMED)


Primary bone tumors, benign and malignant, account for an important percentage of neoplasms in the pediatric population. According to the National Cancer Institute Surveillance Epidemiology and End Result 1975–1995 program, malignant bone tumors comprise approximately 6 % of childhood cancer, having an average annual incidence rate of 8.7 per million children younger than 20 years of age. According to the report, in the United States each year 650–700 children and adolescents younger than 20 years of age are diagnosed with malignant bone tumors.


Osteoblastic tumors Osteosarcoma Cartilaginous neoplasms Exostosis Chondrosarcoma 


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© Springer Science+Business Media New York 2012

Authors and Affiliations

  1. 1.Department of Internal MedicineUniversity of Iowa Hospitals and ClinicsIowa CityUSA
  2. 2.Department of PathologyFroedtert Hospital/Medical College of WisconsinMilwaukeeUSA

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