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Regenerative Therapies for Liver Diseases

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Book cover Regenerative Medicine and Cell Therapy

Part of the book series: Stem Cell Biology and Regenerative Medicine ((STEMCELL))

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Abstract

The liver responds to injury or tissue loss by rapid restoration of the original cell mass. The high regenerative capacity is sufficient to restore normal volume and function in most forms of acute liver injury and medical interventions are not required. For the development of regenerative therapies a fundamental understanding of these regenerative principles in the liver is required. In this chapter, we discuss the emerging medical approaches for acute liver failure, chronic liver failure, and hereditary liver diseases, which are based on technologies, such as (stem) cell therapy, tissue engineering, bio-artificial devices or gene therapies.

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Authors and Affiliations

  1. Junior Research Group “Stem Cell Biology”, Cluster of Excellence REBIRTH, Hannover Medical School, Hannover, Germany

    Amar Deep Sharma & Tobias Cantz

  2. Department of Gastroenterology Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

    Ina Rittelmeyer & Michael Ott

  3. TWINCORE, Centre for Experimental and Clinical Infection Research, A joint venture between the Hannover Medical School (MHH) and the Helmholtz Centre for Infection Research (HZI), Hannover, Germany

    Ina Rittelmeyer & Michael Ott

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  1. Amar Deep Sharma
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  2. Ina Rittelmeyer
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  3. Tobias Cantz
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  4. Michael Ott
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Correspondence to Michael Ott .

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Editors and Affiliations

  1. Royan Institute, Department of Developmental Biology, University of Science and Culture, PO Box 19395-4644, Tehran, Iran

    Hossein Baharvand

  2. , Regenerative Medicine, Royan Institute for Stem Cell Biology an, P.O. Box: 19395-4644, Tehran, Iran

    Nasser Aghdami

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Sharma, A.D., Rittelmeyer, I., Cantz, T., Ott, M. (2013). Regenerative Therapies for Liver Diseases . In: Baharvand, H., Aghdami, N. (eds) Regenerative Medicine and Cell Therapy. Stem Cell Biology and Regenerative Medicine. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-098-4_10

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