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Magnesium in Human Health and Disease pp 139–148Cite as

Magnesium and Diabetes Prevention

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Abstract

In Japan, the respective prevalence of probable and possible diabetes increased respectively from 6.9 to 8.9 and from 6.8 to 13.2 million cases between 1997 and 2007 [1]. Probable diabetes cases are characterized by either high levels of glycated hemoglobin (≥ 6.1 %) or by receiving medication for type 2 diabetes. Possible diabetes cases are characterized by glycated hemoglobin levels ranging from 5.6 % to 6.1 % [1]. Within populations of Japanese men and women aged over 50 years, the prevalence of probable and possible diabetes has been reported to be as high as 30–40 % [1]. Although the prevalence of obesity (an important risk factor of type 2 diabetes) is lower in Japanese than in Western populations [2], the prevalence of type 2 diabetes is not dramatically lower [3]. While these epidemic proportions of type 2 diabetes among Japanese have mainly been attributed to genetic differences between Asian and Caucasian populations [4], some limited evidence also suggests the influence of environmental factors, such as diet. For example, magnesium is involved in glucose homeostasis and insulin action [5], and its protective effect against type 2 diabetes has been demonstrated by several prospective studies, including one involving a Japanese population.

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Authors and Affiliations

  1. Department of Epidemiology and Prevention, Clinical Research Center, National Center for Global Health and Medicine, 1-21-1 Toyama Shinjuku-ku, Tokyo, 162-8655, Japan

    Akiko Nanri Ph.D. (Chief) & Tetsuya Mizoue M.D., Ph.D. (Director)

Authors
  1. Akiko Nanri Ph.D.
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  2. Tetsuya Mizoue M.D., Ph.D.
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Correspondence to Akiko Nanri Ph.D. .

Editor information

Editors and Affiliations

  1. Arizona Health Science Center, Mel and Enid Zuckerman, University of Arizona, 1295 N. Martin, Tucson, 85724-5155, Arizona, USA

    Ronald Ross Watson

  2. Dept. Nutrition & Dietetics, King's College, Stamford St. 150, London, SE1 9NH, United Kingdom

    Victor R. Preedy

  3. Division of Health Promotion Sciences, Mel and Enid Zuckerman, University of Arizona, 1295 N. Martin Avenue, Tucson, 85724, Arizona, USA

    Sherma Zibadi

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Nanri, A., Mizoue, T. (2013). Magnesium and Diabetes Prevention. In: Watson, R., Preedy, V., Zibadi, S. (eds) Magnesium in Human Health and Disease. Nutrition and Health. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-62703-044-1_9

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  • DOI: https://doi.org/10.1007/978-1-62703-044-1_9

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-62703-043-4

  • Online ISBN: 978-1-62703-044-1

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