Androgen Decline in the Aging Male: Making Sense of the “Male Menopause”
Testosterone often declines as men age, and this decline may be associated with a number of specific physical changes that affect quality of life and life expectancy. Unlike the female menopause, which is rapid and well described, this “male menopause” may be gradual, and discerning symptoms that are actually caused by testosterone deficiency and improved by testosterone replacement can be challenging. This chapter will review Androgen Decline in the Aging Male (ADAM), also known as Testosterone Deficiency Syndrome (TDS) and cover symptoms, diagnosis, treatment options, and precautions.
KeywordsProstate Cancer Erectile Dysfunction Testosterone Level Serum Testosterone Free Testosterone
- 26.Aversa A, Bruzziches R, Francomano D, et al. Effects of testosterone undecanoate on cardiovascular risk factors and atherosclerosis in middle-aged men with late-onset hypogonadism and metabolic syndrome: results from a 24-month, randomized, double-blind, placebo-controlled study. J Sex Med. 2010;7:3495–503.PubMedCrossRefGoogle Scholar
- 30.Buvat J, Montorsi F, Maggi M, et al. Hypogonadal men nonresponders to the PDE5 inhibitor tadalafil benefit from normalization of testosterone levels with a 1% hydroalcoholic testosterone gel in the treatment of erectile dysfunction (TADTEST study). J Sex Med. 2011;8:284–93.PubMedCrossRefGoogle Scholar