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Cytoskeleton and Human Disease pp 103–121Cite as

The Actin Cytoskeleton and Membrane Organisation in T Lymphocytes

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Abstract

The dynamics of the actin cytoskeleton are under the strong influence of signalling events at the membrane and membrane domains. In T cells, the importance of actin-membrane-interactions is critical in the processes of T cell activation and migration. If the coordination of actin and the T lymphocyte membrane are out of order, it can compromise the human immune system and lead to immunodeficiencies.

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Authors and Affiliations

  1. Centre for Vascular Research, University of New South Wales, 2052, Sydney, Kensington (NSW), Australia

    Rhea Cornely & Katharina Gaus

  2. Faculty of Pharmacy, University of Sydney, Sydney, NSW, Australia

    Thomas Grewal

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  1. Rhea Cornely
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  2. Thomas Grewal
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  3. Katharina Gaus
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Correspondence to Katharina Gaus .

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  1. Australia for Medical Research, Iron Metabolism Program, Children's Cancer Institute, Randwick, New South Wales, Australia

    Maria Kavallaris

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Cornely, R., Grewal, T., Gaus, K. (2012). The Actin Cytoskeleton and Membrane Organisation in T Lymphocytes. In: Kavallaris, M. (eds) Cytoskeleton and Human Disease. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61779-788-0_5

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