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The Generation of Disease-Specific Cell Lines and Their Use for Developing Drug Therapies

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Nuclear Reprogramming and Stem Cells

Part of the book series: Stem Cell Biology and Regenerative Medicine ((STEMCELL))

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Abstract

Regenerative medicine has become an increasingly important field of research in contemporary bioscience. The importance of this research area is based on demographic changes in our aging societies and driven by the establishment of human embryonic stem cell lines. Disease-specific cell lines can be derived by various strategies, all aiming to enhance the understanding of disease at a cellular level and opening doors for drug discovery and development. The long-term goal of stem cells could lie in the potential to replace tissue and organs susceptible to age-related degeneration or traumatic injury.

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Author information

Authors and Affiliations

  1. Department of Medical and Molecular Genetics, King’s College London School of Medicine, 8th Floor Tower Wing, Guy’s Hospital, Great Maze Pond, London, SE1 9RT, UK

    Stefanie Gögel

  2. Wolfson Centre for Age-Related Diseases, Guy’s Campus, King’s College London, London, UK

    Stephen L. Minger

Authors
  1. Stefanie Gögel
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  2. Stephen L. Minger
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Corresponding author

Correspondence to Stefanie Gögel .

Editor information

Editors and Affiliations

  1. Leeds Institute of Genetics,, Health & Therapeutics, University of Leeds, Leeds, LS2 9JT, United Kingdom

    Justin Ainscough

  2. Inst. Frontier Medical Sciences, Kyoto University, Kawahara-cho 53, Kyoto, 606-8507, Japan

    Shinya Yamanaka

  3. Inst. Frontier Medical Sciences, Kyoto University, Kawahara-cho 53, Kyoto, 606-8507, Japan

    Takashi Tada

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Gögel, S., Minger, S.L. (2011). The Generation of Disease-Specific Cell Lines and Their Use for Developing Drug Therapies. In: Ainscough, J., Yamanaka, S., Tada, T. (eds) Nuclear Reprogramming and Stem Cells. Stem Cell Biology and Regenerative Medicine. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61779-225-0_17

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