Abstract
Atopy, or atopic dermatitis is a common allergic skin condition affecting dogs in North America. As a result of type-I hypersensitivity reaction, individuals afflicted with atopy experience intense pruritus, bacterial and fungal skin infection, and lifelong therapy to decrease the severity of the disease. Oxidative stress resulting from and being caused by allergic inflammation is thought to perpetuate skin irritation and magnify the severity of disease manifestation. Traditional anti-inflammatory and immune-suppressant therapies are effective in most cases at controlling signs of disease but often carry significant costs and side effects for the patient. Recent interest in alternative or complementary therapies for atopy has resulted in proliferation of dermatology-specific antioxidant preparations for veterinary patients. Compounds of particular interest include proanthocyanidins, omega three fatty acids, alpha lipoic acid, and spirulina. As clinical experience with the use of such treatment alternatives grows and as this experience gathers support by scientific research, antioxidants may become commonplace adjunct therapy in the treatment of many allergic skin conditions.
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Kuck, J. (2011). Nutrient Selection in the Management of Canine Atopic Dermatitis. In: Mandelker, L., Vajdovich, P. (eds) Studies on Veterinary Medicine. Oxidative Stress in Applied Basic Research and Clinical Practice. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-61779-071-3_10
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DOI: https://doi.org/10.1007/978-1-61779-071-3_10
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