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Opioid Receptors: The Early Years

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The Opiate Receptors

Part of the book series: The Receptors ((REC))

Abstract

Opioid receptors were first demonstrated long after they were proposed. Pharmacological studies of opiates in patients and animal models have typically predicted concepts subsequently confirmed at the molecular level. The initial ­binding of opiates, the identification of the opioid peptides and the concept of opioid receptor multiplicity are excellent examples. This review will discuss many of these early studies in the context of our current understanding of opioid action.

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    Gavril W. Pasternak

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Correspondence to Gavril W. Pasternak .

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  1. , Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, 10065, New York, USA

    Gavril W. Pasternak

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Pasternak, G.W. (2011). Opioid Receptors: The Early Years. In: Pasternak, G. (eds) The Opiate Receptors. The Receptors. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-993-2_4

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