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The Opiate Receptors pp 441–485Cite as

Role of Opioid Receptors in Narcotic Tolerance/ Dependence

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Part of the book series: The Receptors ((REC))

Abstract

The signal feature of opioid drugs is their ability to induce tolerance and dependence when given chronically to humans or experimental animals. Tolerance may be defined as a state in which the dose of drug required to achieve a given effect is larger than normal. Dependence is a state in which regular doses of the drug are required to prevent withdrawal symptoms.

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Authors
  1. Andrew P. Smith
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  2. Ping-Yee Law
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  3. Horace H. Loh
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Editors and Affiliations

  1. Memorial Sloan-Kettering Cancer Center and Cornell University Medical College, New York, New York, USA

    Gavril W. Pasternak

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Smith, A.P., Law, PY., Loh, H.H. (1988). Role of Opioid Receptors in Narcotic Tolerance/ Dependence. In: Pasternak, G.W. (eds) The Opiate Receptors. The Receptors. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-990-1_13

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  • DOI: https://doi.org/10.1007/978-1-60761-990-1_13

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