Mobilization of Stem Cells/Progenitor Cells by Physical Activity

  • Patrick Wahl
  • Wilhelm BlochEmail author
Part of the Stem Cell Biology and Regenerative Medicine book series (STEMCELL)


A number of publications have provided evidence that exercise and physical activity are linked to the activation, mobilization, and differentiation of various types of stem cells. Exercise may improve organ regeneration and function. This review characterizes different stem and progenitor cells and their sources and summarizes mechanisms by which exercise contributes to stem-cell-induced regeneration and adaptation in different tissues. The principal mechanisms, especially stimuli induced by physical activity, of stem and progenitor cell activation/mobilization are described. In addition, we discuss whether exercise may improve and support stem cell transplantation.


Exercise Mechanical stimuli Hormonal stimuli Metabolic stimuli Stem cell mobilization 


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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Institute of Cardiovascular Research and Sport MedicineGerman Sport UniversityCologneGermany
  2. 2.Institute of Training Science and Sport InformaticsCologneGermany
  3. 3.The German Research Center of Elite SportCologneGermany
  4. 4.Institute of Cardiovascular Research and Sport MedicineThe German Research Center of Elite Sport, German Sport UniversityCologneGermany

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