Diaphragmatic Pacing in Infants and Children with Congenital Central Hypoventilation Syndrome

  • Anthony C. ChinEmail author
  • Donald B. Shaul
  • Pallavi P. Patwari
  • Thomas G. Keens
  • Anna S. Kenny
  • Debra E. Weese-Mayer
Part of the Respiratory Medicine book series (RM)


Artificially supported ventilation is a mainstay of care for children with congenital central hypoventilation syndrome (CCHS). Determining the optimal type and duration of ventilatory support for each individual should proceed with careful consideration. Diaphragm pacing offers a number of advantages over positive pressure ventilation as an alternative method for providing artificial ventilatory support to children with chronic respiratory failure. With diaphragm pacing, the pacer sends electrical current directly to the phrenic nerves. Negative pressure ventilation is created by the child’s diaphragm rather than by an external piston or blower of the mechanical ventilator. These benefits can substantially improve the quality of life of these patients and potentially optimize both behavioral and neurocognitive development in these children, especially in toddlers. This chapter explores important considerations including the pros and cons of diaphragmatic pacing.


Phrenic Nerve Positive Pressure Ventilation Subcutaneous Pocket Phrenic Nerve Stimulation Single Lung Ventilation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2012

Authors and Affiliations

  • Anthony C. Chin
    • 1
    Email author
  • Donald B. Shaul
    • 2
  • Pallavi P. Patwari
    • 3
  • Thomas G. Keens
    • 4
  • Anna S. Kenny
    • 3
  • Debra E. Weese-Mayer
    • 3
  1. 1.Department of Pediatric Surgery, Ann and Robert H. Lurie Children’s HospitalNorthwestern University Feinberg School of MedicineChicagoUSA
  2. 2.Southern California Kaiser Permanente Medical Group, Pediatric Surgery and UrologyLos Angeles Medical CenterLos AngelesUSA
  3. 3.Center for Autonomic Medicine in Pediatrics Ann and Robert H. Lurie Children’s HospitalNorthwestern University Feinberg School of MedicineChicagoUSA
  4. 4.Department of Pediatric Pulmonology, Children’s Hospital Los AngelesKeck School of Medicine of the University of Southern CaliforniaLos AngelesUSA

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