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Metabolic Consequences of Sleep Disorders

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Sleep Disordered Breathing in Children

Part of the book series: Respiratory Medicine ((RM))

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Abstract

In parallel with the explosive increase in obesity rates among children, exploration of potential associations between sleep and obesity has been now extensively pursued, particularly in the wake of our increased understanding of sleep and circadian clocks as critical metabolic regulators. In this chapter, I initially examine some of the evidence on such proposed associations. The increase in the prevalence of overweight and obese children is also anticipated to be deleterious to global health outcomes and life expectancy, and among such consequences, it can increase the risk of obstructive sleep apnea, and such issue is therefore critically assessed as well. Since both conditions can be viewed as low-grade inflammatory disorders, coexistence of obesity and sleep apnea could further interact to amplify their putative effects on metabolic regulation.

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Acknowledgments

David Gozal is supported by National Institutes of Health grants HL-65270 and HL-086662.

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Authors and Affiliations

  1. Department of Pediatrics, Comer Children’s Hospital, Pritzker School of Medicine, The University of Chicago, 5721 South Maryland Avenue, MC 8000, Suite K-160, Chicago, IL, 60637, USA

    David Gozal MD

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  1. David Gozal MD
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Correspondence to David Gozal MD .

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Editors and Affiliations

  1. Section of Sleep Medicine, Pritzker School of Medicine, Department of Pediatrics, S. Maryland Ave. 5721, Chicago, 60637, Illinois, USA

    Leila Kheirandish-Gozal

  2. Pritzker School of Medicine, Comer Children's Hospital, Department of Pediatrics, S. Maryland Ave. 5721, Chicago, 60637, Illinois, USA

    David Gozal

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Gozal, D. (2012). Metabolic Consequences of Sleep Disorders. In: Kheirandish-Gozal, L., Gozal, D. (eds) Sleep Disordered Breathing in Children. Respiratory Medicine. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-725-9_36

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  • DOI: https://doi.org/10.1007/978-1-60761-725-9_36

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-60761-724-2

  • Online ISBN: 978-1-60761-725-9

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