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Cardiovascular Implications

  • Rakesh BhattacharjeeEmail author
  • Leila Kheirandish-Gozal
Chapter
Part of the Respiratory Medicine book series (RM)

Abstract

The physiological aberrations induced by obstructive sleep apnea (OSA) in children, namely the abnormalities in gas exchange, frequent cortical arousals, and fluxes of intrathoracic pressure induced by respiration in the setting of an occluded airway, can have significant ramifications of homeostasis in several organs including the cardiovascular system. In this chapter, the evidence supporting cardiovascular dysfunction in pediatric OSA is presented; prompting the hypothesis that untreated OSA may induce end-organ injury to the cardiovascular system thereby promoting long-term cardiovascular disease.

Keywords

Obstructive Sleep Apnea Heart Rate Variability Continuous Positive Airway Pressure Right Ventricle Obstructive Sleep Apnea Patient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Notes

Acknowledgments

Funding sources: Leila Kheirandish-Gozal is supported by NIH grant K12 HL-090003.

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Copyright information

© Springer Science+Business Media New York 2012

Authors and Affiliations

  1. 1.Divisions of Pulmonary and Sleep Medicine, Department of PediatricsThe University of ChicagoChicagoUSA
  2. 2.Section of Sleep Medicine, Department of Pediatrics, Pritzker School of MedicineThe University of ChicagoChicagoUSA

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