Apnea of Prematurity

  • Christian F. PoetsEmail author
Part of the Respiratory Medicine book series (RM)


Almost every extremely low gestational age neonate (ELGAN) is affected by apnea of prematurity (AOP). Yet its precise pathophysiology is incompletely understood. In this chapter, data from observational studies will be reviewed in an attempt better to understand the mechanisms involved in the pathophysiology of AOP, focusing on bradycardia and hypoxemia because they, and not apnea duration, are relevant to the well-being of an infant. Based on these data, this chapter will review the current knowledge on the prevention and treatment—including prone positioning, continuous positive airway pressure (CPAP), nasal intermittent positive pressure ventilation (N-IPPV), and caffeine—of AOP.


Continuous Positive Airway Pressure Preterm Infant Lung Volume Functional Residual Capacity Intermittent Hypoxia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer Science+Business Media New York 2012

Authors and Affiliations

  1. 1.Department of NeonatologyTuebingen University HospitalTuebingenGermany

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