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Motility Problems in Developmental Disorders: Cerebral Palsy, Down Syndrome, William Syndrome, Familial Dysautonomia, and Mitochondrial Disorders

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Pediatric Neurogastroenterology

Part of the book series: Clinical Gastroenterology ((CG))

Abstract

Motility disorders often complicate the medical history of primary diseases. High prevalences of gastroesophageal reflux disease (GERD) and swallowing disorders are described in patients affected by cerebral palsy, familial dysautonomia, and Williams syndrome; Down syndrome has been associated with a high incidence of GERD and Hirschsprung disease, and many gastrointestinal complaints have been described in patients affected by mitochondrial disorders. Gastrointestinal motility problems represent an important cause of morbidity and sometimes mortality in patients affected by developmental disorders. Nevertheless, they are often neglected because priority is mainly given to other clinical aspects of these pathologies. However, early diagnosis and optimal care is required to improve the quality of life and minimize morbidity and mortality of these patients.

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Authors and Affiliations

  1. Pediatric Gastoenterology Division, Pediatrics Department, University of Naples “Federico II”, Via Pansini No 5, Naples, 80131, Italy

    Annamaria Staiano M.D. & Massimo Martinelli M.D.

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  1. Annamaria Staiano M.D.
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  2. Massimo Martinelli M.D.
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Correspondence to Annamaria Staiano M.D. .

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Editors and Affiliations

  1. Sainte-Justine Hospital, Department of Pediatrics, Division of Pediatric Gastroenterology, Université de Montréal, Montreal, H3T 1C5, Québec, Canada

    Christophe Faure

  2. Nationwide Children's Hospital, Division of Pediatric Gastroenterology, The Ohio State University, Columbus, 43205, Ohio, USA

    Carlo Di Lorenzo

  3. Gastroenterology and Neural Development, University College London, Institute of Child Health, Great Ormond Street Hospital for Children, London, WC1N 1EH, United Kingdom

    Nikhil Thapar

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Staiano, A., Martinelli, M. (2013). Motility Problems in Developmental Disorders: Cerebral Palsy, Down Syndrome, William Syndrome, Familial Dysautonomia, and Mitochondrial Disorders. In: Faure, C., Di Lorenzo, C., Thapar, N. (eds) Pediatric Neurogastroenterology. Clinical Gastroenterology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-709-9_24

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  • DOI: https://doi.org/10.1007/978-1-60761-709-9_24

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