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Pain in Parkinson’s Disease: Pathophysiology, Classification, and Clinical Approach

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Part of the book series: Current Clinical Neurology ((CCNEU))

Abstract

Pain is a frequent yet underrecognized symptom of Parkinson’s disease (PD). Although routine clinical neurological examination generally does not reveal any abnormality of sensation in persons with PD, objective abnormalities of proprioceptive function and sensorimotor integration have been demonstrated with sophisticated testing. Painful symptoms pose a considerable diagnostic and therapeutic challenge to the clinician. For diagnostic purposes, it is helpful to classify painful or unpleasant sensory symptoms into one or more of the following five categories: musculoskeletal pain, radicular or neuropathic pain, dystonia-related pain, akathitic discomfort, or primary, central parkinsonian pain. The identification of parkinsonian pain is vitally important for the effective diagnosis and treatment of pain in PD.

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Hess, C., Ford, B. (2013). Pain in Parkinson’s Disease: Pathophysiology, Classification, and Clinical Approach. In: Pfeiffer, R.F., Bodis-Wollner, I. (eds) Parkinson’s Disease and Nonmotor Dysfunction. Current Clinical Neurology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-429-6_24

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