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Autoimmune Endocrine Disorders

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Pediatric Endocrinology

Part of the book series: Contemporary Endocrinology ((COE))

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Abstract

Autoimmune endocrine disorders are common conditions evaluated for and treated by pediatric endocrinologists. Recognition of the underlying autoimmunity associated with the disorders and disease associations is critical to providing appropriate care for these patients. Autoimmune endocrine disorders coexist in recognized syndromes known as the autoimmune polyendocrine syndromes (APS): APS-1 or autoimmune polyendocrinopathy candidiasis and ectodermal dystrophy (APECED) and APS-2. More rare autoimmune endocrine disorders include the immunodysregulation polyendocrinopathy enteropathy X-linked (IPEX) syndrome. This rare disorder presents in infancy with type 1 diabetes and enteropathy. In this chapter, we will discuss the pathophysiology of the autoimmune process, the underlying genetics and disease associations of the autoimmune polyendocrine syndromes, and treatment and screening protocols and briefly touch on rare autoimmune endocrine disorders.

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Authors and Affiliations

  1. Pediatric Endocrinology, Colorado Children’s Hospital, 13123 E. 16th Avenue B265, Aurora, CO, 80045, USA

    Jennifer M. Barker M.D.

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  1. Jennifer M. Barker M.D.
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Correspondence to Jennifer M. Barker M.D. .

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Editors and Affiliations

  1. School of Medicine, Department of Pediatrics, The Johns Hopkins University, 600 North Wolfe St., Baltimore, 21287, Maryland, USA

    Sally Radovick

  2. , Department of Pediatrics, Children's Hospital of Buffalo, 219 Bryant St., Buffalo, 14222, New York, USA

    Margaret H. MacGillivray

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Barker, J.M. (2013). Autoimmune Endocrine Disorders. In: Radovick, S., MacGillivray, M. (eds) Pediatric Endocrinology. Contemporary Endocrinology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-395-4_31

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  • DOI: https://doi.org/10.1007/978-1-60761-395-4_31

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-60761-394-7

  • Online ISBN: 978-1-60761-395-4

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