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Precocious Puberty: Clinical Management

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Pediatric Endocrinology

Part of the book series: Contemporary Endocrinology ((COE))

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Abstract

Precocious puberty has been a focus of interest for both the pediatric ­endocrinologist and the primary pediatrician for many years. Thirty years ago (1980s), the development and application of GnRH agonist (GnRHa) therapy to treat central precocious puberty significantly changed our approach to this disorder. More recently, application of molecular biological techniques has provided us with a better understanding of the intricacies of the regulation of gonadotropin and sex-steroid production characteristic of normal pubertal development and provided us with the tools to elucidate the etiologies of previously uncharacterized disorders of precocious puberty.

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Rodriguez, H., Dougan, G.C. (2013). Precocious Puberty: Clinical Management. In: Radovick, S., MacGillivray, M. (eds) Pediatric Endocrinology. Contemporary Endocrinology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-395-4_23

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