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Treatment of Cutaneous T-cell Lymphomas

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Neoplastic Hematopathology

Part of the book series: Contemporary Hematology ((CH))

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Abstract/Scope of the Chapter

Cutaneous T-cell lymphomas (CTCLs) are a diverse group of non-Hodgkin’s lymphomas presenting as skin lesions containing malignant, skin-homing T cells. Mycosis fungoides (MF) and the leukemic variant, Sézary Syndrome (SS), are the most common CTCLs and the main focus of this chapter. Skin-directed therapy is sufficient for early patch/plaque MF which may remain indolent for many years. Biological response modifiers and phototherapy are added for SS, and for refractory or progressive MF. Experimental agents that block key pathways and targeted therapies are under development and will provide more options.

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Author information

Authors and Affiliations

  1. Department of Dermatology, University of Texas Medical School at Houston, Houston, TX, USA

    Katherine M. Cox

  2. Department of Dermatology, M. D. Anderson Cancer Center, The University of Texas, Houston, TX, USA

    Madeleine Duvic

Authors
  1. Katherine M. Cox
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  2. Madeleine Duvic
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Corresponding author

Correspondence to Katherine M. Cox .

Editor information

Editors and Affiliations

  1. M.D. Anderson Cancer Center, The University of Texas, Holcombe Blvd. 1515 , Houston, 77030, U.S.A.

    Dan Jones

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© 2010 Humana Press, a part of Springer Science+Business Media, LLC

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Cox, K.M., Duvic, M. (2010). Treatment of Cutaneous T-cell Lymphomas. In: Jones, D. (eds) Neoplastic Hematopathology. Contemporary Hematology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-384-8_25

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  • DOI: https://doi.org/10.1007/978-1-60761-384-8_25

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  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-60761-383-1

  • Online ISBN: 978-1-60761-384-8

  • eBook Packages: MedicineMedicine (R0)

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