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Sexual Differentiation of the Brain: Genetic, Hormonal and Trophic Factors

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Book cover Mammalian Brain Development

Part of the book series: Contemporary Neuroscience ((CNEURO))

Abstract

The current hypothesis to explain the sexual dimorphism of structure and function in the brain of vertebrates maintains that these differences are produced by the interaction of genetic mechanisms and gonadal hormones. In this chapter we summarize the evidence from our laboratory, as well as other laboratories analyzing the mechanisms that control sexually differentiated growth of axons in hypothalamic neurons in vitro.

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Acknowledgments

Work from the authors’ laboratory was supported by grants from Agencia Córdoba Ciencia, Agencia Nacional de Promoción Científica y Tecnológica, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) of Argentina and the European Commission. H.F.C. and M.J.C are career members of CONICET.

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  1. Instituto de Investigación Médica Mercedes y Martin Ferreyra, Instituto Ferreyra, Casilla de Correo 389, 5000, Córdoba, Argentina

    Hugo F. Carrer

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Correspondence to Hugo F. Carrer .

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    Carrer, H.F., Cambiasso, M.J. (2009). Sexual Differentiation of the Brain: Genetic, Hormonal and Trophic Factors. In: Janigro, D. (eds) Mammalian Brain Development. Contemporary Neuroscience. Humana Press. https://doi.org/10.1007/978-1-60761-287-2_1

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