Skip to main content

Cochlear and Non-cochlear Age-Related Hearing Loss and Tinnitus

  • Chapter
Textbook of Tinnitus
  • 5447 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Notes

  1. 1.

    Presbycusis: Loss of hearing associated with aging; manifest as reduced ability to perceive or discriminate sounds; the pattern and age of onset vary (Stedman’s Electronic Medical Dictionary).

  2. 2.

    Phonemic regression: a decrease in intelligibility of speech out of proportion to the pure tone hearing loss associated with aging (Stedman’s Electronic Medical Dictionary).

  3. 3.

    Spontaneous hypertensive rats: Rats with genetic predisposition for greater increase in blood pressure with age than normal.

Abbreviations

ARHI:

Age-related hearing impairment

EPSP:

Excitatory postsynaptic potentials

GABA:

Gamma amino butyric acid

References

  1. Spoor A (1967) Presbycusis values in relation to noise induced hearing loss. Int Audiol 6:48–57.

    Article  Google Scholar 

  2. Møller MB (1981) Hearing in 70 and 75 year-old people. results from a cross-sectional and longitudinal population study. Am J Otolaryngol 2:22–9.

    Article  PubMed  Google Scholar 

  3. Johnson KR, LC Erway, SA Cook et al. (1997) A major gene affecting age-related hearing loss in C57BL/6J mice. Hear Res 114:83–92.

    Article  PubMed  CAS  Google Scholar 

  4. Topsakal V, G Van Camp and P Van de Heyning (2005) Genetic testing for hearing impairment. B-ENT 1:125–35.

    Google Scholar 

  5. Fransen E, L Van Laer, N Lemkens et al. (2004) A novel Z-score-based method to analyze candidate genes for age-related hearing impairment. Ear Hear 25:133–41.

    Article  PubMed  Google Scholar 

  6. Gates G, A, JCJ Cooper, WB Kannel et al. (1990) Hearing in the elderly: the Framingham cohort, 1983–1985. Part I. Basic audiometric test results. Ear Hear 11:247–56.

    Google Scholar 

  7. Lee FS, LJ Matthews, JR Dubno et al. (2005) Longitudinal study of pure-tone thresholds in older person. Ear Hear 26:1–11.

    Article  PubMed  Google Scholar 

  8. Jerger J, R Chmiel, B Stach et al. (1993) Gender affects audiometric shape in presbyacusis. J Am Acad Audiol 4(1):42–9

    PubMed  CAS  Google Scholar 

  9. Borg E and AR Møller (1978) Noise and blood pressure: Effects on lifelong exposure in the rat. Acta Physiol Scand 103:340–42.

    Article  PubMed  CAS  Google Scholar 

  10. Borg E (1982) Noise induced hearing loss in normotensive and spontaneously hypertensive rats. Hear Res 8:117–30.

    Article  PubMed  CAS  Google Scholar 

  11. Willott JF, TH Chisolm and JJ Lister (2001) Modulation of presbycusis: current status and future directions. Audiol Neurotol 6:231–49.

    Article  CAS  Google Scholar 

  12. Do Carmo LC, JA Médicis da Silveira, SA Marone et al. (2008) Audiological study of an elderly Brazilian population. Braz J Otorhinolaryngol 74:342–9.

    PubMed  Google Scholar 

  13. Nondahl DM, KJ Criuckshanks, TL Wiley et al. (2002) Prevalence and 5-year incidence of tinnitus among older adults: the epidemiology of hearing loss study. J Am Acad Audiol 13:323–31.

    PubMed  Google Scholar 

  14. Rosenhall U and AK Karlsson (1991) Tinnitus in old age. Scand. Audiol 20:165–71.

    Article  PubMed  CAS  Google Scholar 

  15. Ahmad N and M Seidman (2004) Tinnitus in the older adult: epidemiology, pathophysiology and treatment options. Drugs Aging 21:297–305.

    Article  PubMed  Google Scholar 

  16. Demeester K, A van Wieringen, JJ Hendrickx et al. (2007) Prevalence of tinnitus and audiometric shape. B-ENT Suppl 7:37–49.

    Google Scholar 

  17. Borghi C, C Brandolini, MG Prandin et al. (2005) Prevalence of tinnitus in patients withhypertension and the impact of different anti hypertensive drugs on the incidence of tinnitus: A prospective, single-blind, observational study. Current Therapeutic Research 66:420–32.

    Article  CAS  Google Scholar 

  18. Johnsson LG and HL Hawkins (1972) Sensory and neural degeneration with aging, as seen in microdissections of the human inner ear. Ann Otol Rhinol Laryngol 81:179–93.

    PubMed  CAS  Google Scholar 

  19. Møller AR (2006) Hearing: Anatomy, Physiology, and Disorders of the Auditory System, 2nd Ed. 2006, Amsterdam: Academic Press.

    Google Scholar 

  20. Miller JM, CS Watson and WP Covell (1963) Deafening effects of noise on the cat. Acta Oto Laryng Suppl. 176 1–91.

    Google Scholar 

  21. Canlon B, E Borg and A Flock (1988) Protection against noise trauma by pre-exposure to a low level acoustic stimulus. Hear Res 34:197–200.

    Article  PubMed  CAS  Google Scholar 

  22. Borg E (1981) Noise, hearing, and hypertension. Scand Audiol 10:125–6.

    Article  PubMed  CAS  Google Scholar 

  23. Borg E (1982) Noise induced hearing loss in rats with renal hypertension. Hear Res 8:93–9.

    Article  Google Scholar 

  24. Hultcrantz M, R Simonoska and AE Stenberg (2006) Estrogen and hearing: a summary of recent investigations. Acta Otolaryngol 126:10–4.

    Article  PubMed  CAS  Google Scholar 

  25. Elkind-Hirsch KE, WR Stoner, BA Stach et al. (1992) Estrogen influences auditory brainstem responses during the normal menstrual cycle. Hear Res 60:143–8.

    Article  PubMed  CAS  Google Scholar 

  26. Malyala A, MJ Kelly and OK Rønnekleiv (2005) Estrogen modulation of hypothalamic neurons: activation of multiple signaling pathways and gene expression changes. Steroids 70:397–406.

    Article  PubMed  CAS  Google Scholar 

  27. Pujol R, G Rebillard, PJ L. et al. (1990) Glutamate neurotoxicity in the cochlea: a possible consequence of ischaemic or anoxic conditions occurring in ageing. Acta Otolaryngol Suppl. 476:32–6.

    PubMed  CAS  Google Scholar 

  28. Mukherjee J, BT Christian, KA Dunigan et al. (2002) Brain imaging of 18F-fallypride in normal volunteers: blood analysis, distribution, test-retest studies, and preliminary assessment of sensitivity to aging effects on dopamine D-2/D-3 receptors. Synapse 46:170–88.

    Article  PubMed  CAS  Google Scholar 

  29. Caspary DM, A Raza, Lawhorn et al. (1990) Immunocytochemical and neurochemical evidence for age-related loss of GABA in the inferior colliculus: Implications for neural presbycusis. J Neurosci 10:2363–72.

    Google Scholar 

  30. Syka J (2002) Plastic changes in the central auditory system after hearing loss, restoration of function, and during learning. Physiol Rev 82:601–36.

    PubMed  Google Scholar 

  31. Mazelova J, J Popelar and J Syka (2003) Auditory function in presbycusis: peripheral vs. central changes. Exp Gerontol 38:87–94.

    Article  PubMed  Google Scholar 

  32. Spoendlin H and A Schrott (1989) Analysis of the human auditory nerve. Hear Res 43:25–38.

    Article  PubMed  CAS  Google Scholar 

  33. Møller AR (2006) Neural plasticity and disorders of the nervous system. 2006, Cambridge: Cambridge University Press

    Book  Google Scholar 

  34. Podoshin L, J Ben-David and CB Teszler (1997) Pediatric and Geriatric Tinnitus. Int Tinnitus J 3:101–3.

    PubMed  Google Scholar 

  35. Rubinstein B, T Österberg and U Rosenhall (1992) Longitudinal fluctuations in tinnitus reported by an elderly population. J Audiol Med 1:149–55.

    Google Scholar 

  36. Khaw KT (1997) Epidemiological aspects of ageing. Philos Trans R Soc Lond B Biol Sci 352:1829–35.

    Article  PubMed  CAS  Google Scholar 

  37. Coles R, (2000) Medicolegal issues, in Tinnitus Handbook, R Tyler, Editor. 2000, Singular Publishing: San Diego. 399–417.

    Google Scholar 

  38. Henry JA, M Meikle and A Gilbert, (1999) Audiometric correlates of tinnitus pitch, in Proceedings of the Sixth International Tinnitus Semminar, J Hazell, Editor. The Tinnitus and Hyperacusis Centre: London. 51–7.

    Google Scholar 

  39. Caspary DM, JC Milbrandt and RH Helfert (1995) Central auditory aging: GABA changes in the inferior colliculus. Exp. Gerontol 30:349–60.

    Article  PubMed  CAS  Google Scholar 

  40. Fillit H, DT Nash, T Rundek et al. (2008) Cardiovascular risk factors and dementia. Am J Geriatr Pharmacother 6:100–18.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Aage R. Møller .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Møller, A.R. (2011). Cochlear and Non-cochlear Age-Related Hearing Loss and Tinnitus. In: Møller, A.R., Langguth, B., De Ridder, D., Kleinjung, T. (eds) Textbook of Tinnitus. Springer, New York, NY. https://doi.org/10.1007/978-1-60761-145-5_36

Download citation

  • DOI: https://doi.org/10.1007/978-1-60761-145-5_36

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-60761-144-8

  • Online ISBN: 978-1-60761-145-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics