Skip to main content

Functional Neuroimaging

  • Chapter
Textbook of Tinnitus

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Abbreviations

FDG-PET:

Fluor-deoxy-glucose PET

fMRI:

Functional Magnetic Resonance Imaging

PET:

Positron emission tomography

rCBF:

Regional cerebral blood flow

SPECT:

Single positron emission computed tomography

[15O]-H2O PET:

Positron emission tomography with radioactively labeled water

References

  1. Gardner, A, Pagani, M, Jacobsson, H, Lindberg, G, Larsson, SA, Wagner, A, et al. Differences in resting state regional cerebral blood flow assessed with 99mTc-HMPAO SPECT and brain atlas matching between depressed patients with and without tinnitus. Nucl Med Commun. 2002;23(5):429–39

    Article  PubMed  CAS  Google Scholar 

  2. Shulman, A. A final common pathway for tinnitus – the medial temporal lobe system. Int Tinnitus J. 1995;1(2):115–26

    PubMed  Google Scholar 

  3. Johnsrude, IS, Giraud, AL, Frackowiak, RS. Functional imaging of the auditory system: the use of positron emission tomography. Audiol Neurootol. 2002;7(5):251–76

    Article  PubMed  Google Scholar 

  4. Plewnia, C, Reimold, M, Najib, A, Brehm, B, Reischl, G, Plontke, SK, et al. Dose-dependent attenuation of auditory phantom perception (tinnitus) by PET-guided repetitive transcranial magnetic stimulation. Hum Brain Mapp. 2007;28(3):238–46

    Article  PubMed  Google Scholar 

  5. Reyes, SA, Salvi, RJ, Burkard, RF, Coad, ML, Wack, DS, Galantowicz, PJ, et al. Brain imaging of the effects of lidocaine on tinnitus. Hear Res. 2002;171:43–50

    Article  PubMed  CAS  Google Scholar 

  6. Levine, RA, Abel, M, Cheng, H. CNS somatosensory-auditory interactions elicit or modulate tinnitus. Exp Brain Res. 2003;153(4):643–8

    Article  PubMed  CAS  Google Scholar 

  7. Sanchez, TG, Guerra, GC, Lorenzi, MC, Brandao, AL, Bento, RF. The influence of voluntary muscle contractions upon the onset and modulation of tinnitus. Audiol Neurootol. 2002;7(6):370–5

    Article  PubMed  Google Scholar 

  8. Cacace, AT, Lovely, TJ, McFarland, DJ, Parnes, SM, Winter, DF. Anomalous cross-modal plasticity following posterior fossa surgery: some speculations on gaze-evoked tinnitus. Hear Res. 1994;81:22–32

    Article  PubMed  CAS  Google Scholar 

  9. Giraud, AL, Chery-Croze, S, Fischer, G, Fischer, C, Vighetto, A, Gregoire, MC, et al. A selective imaging of tinnitus. Neuroreport. 1999;10:1–5

    Article  PubMed  CAS  Google Scholar 

  10. Lockwood, AH, Salvi, RJ, Coad, ML, Towsley, ML, Wack, DS, Murphy, BW. The functional neuroanatomy of tinnitus: evidence for limbic system links and neural plasticity. Neurology. 1998;50:114–20

    Article  PubMed  CAS  Google Scholar 

  11. Lockwood, AH, Wack, DS, Burkard, RF, Coad, ML, Reyes, SA, Arnold, SA, et al. The functional anatomy of gaze-evoked tinnitus and sustained lateral gaze. Neurology. 2001;56:472–80

    Article  PubMed  CAS  Google Scholar 

  12. Mirz, F, Pedersen, B, Ishizu, K, Johannsen, P, Ovesen, T, Stodkilde-Jorgensen, H, et al. Positron emission tomography of cortical centers of tinnitus. Hear Res. 1999;134:133–44

    Article  PubMed  CAS  Google Scholar 

  13. Andersson, G, Lyttkens, L, Hirvela, C, Furmark, T, Tillfors, M, Fredrikson, M. Regional cerebral blood flow during ­tinnitus: a PET case study with lidocaine and auditory stimulation. Acta Otolaryngol. 2000;120:967–72

    Article  PubMed  CAS  Google Scholar 

  14. Andersson, G, Juris, L, Classon, E, Fredrikson, M, Furmark, T. Consequences of suppressing thoughts about tinnitus and the effects of cognitive distraction on brain activity in tinnitus patients. Audiol Neurootol. 2006;11(5):301–9

    Article  PubMed  Google Scholar 

  15. Arnold, W, Bartenstein, P, Oestreicher, E, Romer, W, Schwaiger, M. Focal metabolic activation in the predominant left auditory cortex in patients suffering from tinnitus: a PET study with [18F]deoxyglucose. ORL J Otorhinolaryngol Relat Spec. 1996;58:195–9

    Article  PubMed  CAS  Google Scholar 

  16. Wang, H, Tian, J, Yin, D. Positron emission tomography of tinnitus-related brain areas. Zhonghua Er Bi Yan Hou Ke Za Zhi. 2000;35(6):420–4

    PubMed  Google Scholar 

  17. Langguth, B, Eichhammer, P, Kreutzer, A, Maenner, P, Marienhagen, J, Kleinjung, T, et al. The impact of auditory cortex activity on characterizing and treating patients with chronic tinnitus–first results from a PET study. Acta Otolaryngol Suppl. 2006;(556):84–8

    Google Scholar 

  18. Smith, JA, Mennemeier, M, Bartel, T, Chelette, KC, Kimbrell, T, Triggs, W, et al. Repetitive transcranial ­magnetic stimulation for tinnitus: a pilot study. Laryngoscope. 2007;117(3):529–34

    Article  PubMed  Google Scholar 

  19. Eichhammer, P, Hajak, G, Kleinjung, T, Landgrebe, M, Langguth, B. Functional imaging of chronic tinnitus: the use of positron emission tomography. Prog Brain Res. 2007;166:83–8

    Article  PubMed  CAS  Google Scholar 

  20. Yacoub, E, Duong, TQ, Van De Moortele, PF, Lindquist, M, Adriany, G, Kim, SG, et al. Spin-echo fMRI in humans using high spatial resolutions and high magnetic fields. Magn Reson Med. 2003;49(4):655–64

    Article  PubMed  Google Scholar 

  21. Melcher, JR, Sigalovsky, IS, Guinan, JJ, Jr, Levine, RA. Lateralized tinnitus studied with functional magnetic resonance imaging: abnormal inferior colliculus activation. J Neurophysiol. 2000;83:1058–72

    PubMed  CAS  Google Scholar 

  22. Lanting, CP, De, KE, Bartels, H, Van, DP. Functional ­imaging of unilateral tinnitus using fMRI. Acta Otolaryngol. 2008;128(4):415–21

    Article  PubMed  CAS  Google Scholar 

  23. Londero, A, Lefaucheur, JP, Malinvaud, D, Brugieres, P, Peignard, P, Nguyen, JP, et al. Magnetic stimulation of the auditory cortex for disabling tinnitus: preliminary results. Presse Med. 2006;35(2 Pt 1):200–6

    Article  PubMed  Google Scholar 

  24. Smits, M, Kovacs, S, De, RD, Peeters, RR, Van, HP, Sunaert, S. Lateralization of functional magnetic resonance imaging (fMRI) activation in the auditory pathway of patients with lateralized tinnitus. Neuroradiology. 2007;49(8):669–79

    Article  PubMed  Google Scholar 

  25. Attwell, D, Laughlin, SB. An energy budget for signaling in the grey matter of the brain. J Cereb Blood Flow Metab. 2001;21(10):1133–45

    Article  PubMed  CAS  Google Scholar 

  26. Mukamel, R, Gelbard, H, Arieli, A, Hasson, U, Fried, I, Malach, R. Coupling between neuronal firing, field potentials, and FMRI in human auditory cortex. Science. 2005;309(5736):951–4

    Article  PubMed  CAS  Google Scholar 

  27. Nir, Y, Fisch, L, Mukamel, R, Gelbard-Sagiv, H, Arieli, A, Fried, I, et al. Coupling between neuronal firing rate, gamma LFP, and BOLD fMRI is related to interneuronal correlations. Curr Biol. 2007;17(15):1275–85

    Article  PubMed  CAS  Google Scholar 

  28. De Ridder, D, De Mulder, G, Menovsky, T, Sunaert, S, Kovacs, S. Electrical stimulation of auditory and somatosensory cortices for treatment of tinnitus and pain. Prog Brain Res. 2007;166:377–88

    Article  PubMed  Google Scholar 

  29. Jastreboff, PJ. Phantom auditory perception (tinnitus): mechanisms of generation and perception. Neurosci Res. 1990;8:221–54

    Article  PubMed  CAS  Google Scholar 

  30. Møller, AR. Pathophysiology of tinnitus. Otolaryngol Clin North Am. 2003;36:249–66

    Article  PubMed  Google Scholar 

  31. Lockwood, AH, Salvi, RJ, Burkard, RF, Galantowicz, PJ, Coad, ML, Wack, DS. Neuroanatomy of tinnitus. Scand Audiol Suppl. 1999;51:47–52

    PubMed  CAS  Google Scholar 

  32. Plewnia, C, Reimold, M, Najib, A, Reischl, G, Plontke, SK, Gerloff, C. Moderate therapeutic efficacy of positron emission tomography-navigated repetitive transcranial magnetic stimulation for chronic tinnitus: a randomised, controlled pilot study. J Neurol Neurosurg Psychiatry. 2007;78(2):152–6

    Article  PubMed  CAS  Google Scholar 

  33. Mirz, F, Gjedde, A, Ishizu, K, Pedersen, CB. Cortical ­networks subserving the perception of tinnitus–a PET study. Acta Otolaryngol Suppl. 2000;543:241–3

    Article  PubMed  CAS  Google Scholar 

  34. Muhlau, M, Rauschecker, JP, Oestreicher, E, Gaser, C, Rottinger, M, Wohlschlager, AM, et al. Structural brain changes in tinnitus. Cereb Cortex. 2006;16(9):1283–8

    Article  PubMed  CAS  Google Scholar 

  35. Landgrebe M, Langguth B, Rosengarth K, Braun S, Koch A, Kleinjung T, et al. Structural brain changes in tinnitus: Grey matter decrease in auditory and nonauditory brain areas. Neuroimage. 2009;46(1):213–8

    Google Scholar 

  36. Voisin, J, Bidet-Caulet, A, Bertrand, O, Fonlupt, P. Listening in silence activates auditory areas: a functional magnetic resonance imaging study. J Neurosci. 2006;26(1):273–8

    Article  PubMed  CAS  Google Scholar 

  37. Zald, DH, Pardo, JV. The neural correlates of aversive auditory stimulation. Neuroimage. 2002;16:746–53

    Article  PubMed  Google Scholar 

  38. De Ridder, D, De Mulder, G, Walsh, V, Muggleton, N, Sunaert, S, Møller, A. Magnetic and electrical stimulation of the auditory cortex for intractable tinnitus Case report. J Neurosurg. 2004;100(3):560–4

    Article  PubMed  Google Scholar 

  39. Langguth, B, Eichhammer, P, Wiegand, R, Marienhegen, J, Maenner, P, Jacob, P, et al. Neuronavigated rTMS in a patient with chronic tinnitus effects of 4 weeks treatment. Neuroreport. 2003;14:977–80

    Article  PubMed  Google Scholar 

  40. Richter, GT, Mennemeier, M, Bartel, T, Chelette, KC, Kimbrell, T, Triggs, W, et al. Repetitive transcranial magnetic stimulation for tinnitus: a case study. Laryngoscope. 2006;116(10):1867–72

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Berthold Langguth .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Langguth, B., De Ridder, D. (2011). Functional Neuroimaging. In: Møller, A.R., Langguth, B., De Ridder, D., Kleinjung, T. (eds) Textbook of Tinnitus. Springer, New York, NY. https://doi.org/10.1007/978-1-60761-145-5_18

Download citation

  • DOI: https://doi.org/10.1007/978-1-60761-145-5_18

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-60761-144-8

  • Online ISBN: 978-1-60761-145-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics