The Role of Auditory Deprivation

Keypoints

  1. 1.

    Deprivation of input to the auditory system can cause two kinds of change in function: It can alter the balance between inhibition and excitation and can activate neural plasticity.

     
  2. 2.

    Hearing loss of any kind, such as conductive hearing loss or cochlear hearing loss, causes decreased input to the auditory nervous system.

     
  3. 3.

    Noise-induced hearing loss is an example of deprivation of auditory stimulation and overexposure, which in itself may activate neural plasticity.

     
  4. 4.

    Altered balance between inhibition and excitation can change the gain in the auditory system. If the gain is increased, it may cause hyperactivity in the form of tinnitus.

     
  5. 5.

    The effect on the balance between inhibition and excitation is likely to abate when normal input to the auditory system is established.

     
  6. 6.

    Activation of neural plasticity, which may occur because of sensory stimulation, may last after restoring normal sensory stimulation.

     
  7. 7.

    Plastic changes may become permanent, and reversal of neural plasticity may require special actions.

     

Keywords

Tinnitus Sound deprivation Neural plasticity Inhibition Temporal coherence 

References

  1. 1.
    Møller AR and P Rollins (2002) The non-classical auditory system is active in children but not in adults. Neurosci Lett. 319:41–4.PubMedCrossRefGoogle Scholar
  2. 2.
    Møller AR (2006) Hearing: Anatomy, Physiology, and Disorders of the Auditory System, 2nd Ed. Amsterdam: Academic.Google Scholar
  3. 3.
    Møller AR (2006) Neural plasticity and disorders of the nervous system. Cambridge: Cambridge University Press.CrossRefGoogle Scholar
  4. 4.
    Eggermont JJ and LE Roberts (2004) The neuroscience of tinnitus. Trends Neurosci. 27:676–82.PubMedCrossRefGoogle Scholar
  5. 5.
    Møller AR (1984) Pathophysiology of tinnitus. Ann Otol Rhinol Laryngol. 93:39–44.Google Scholar
  6. 6.
    Noreña AJ and JJ Eggermont (2003) Changes in spontaneous neural activity immediately after an acoustic trauma: Implications for neural correlates of tinnitus. Hear Res. 183:137–53.PubMedCrossRefGoogle Scholar
  7. 7.
    Syka J (2002) Plastic changes in the central auditory system after hearing loss, restoration of function, and during learning. Physiol Rev. 82:601–36.PubMedGoogle Scholar
  8. 8.
    Ruggero MA (1992) Responses to sound of the basilar membrane of the mammalian cochlea. Curr Opin Neurobiol. 2:449–56.PubMedCrossRefGoogle Scholar
  9. 9.
    Johnstone BM, R Patuzzi and GK Yates (1986) Basilar membrane measurements and the traveling wave. Hear Res. 22:147–53.PubMedCrossRefGoogle Scholar
  10. 10.
    Møller AR (1977) Frequency selectivity of single auditory nerve fibers in response to broadband noise stimuli. J Acoust Soc Am. 62:135–42.PubMedCrossRefGoogle Scholar
  11. 11.
    Sachs MB and NYS Kiang (1968) Two tone inhibition in auditory nerve fibers. J Acoust Soc Am. 43:1120–8.PubMedCrossRefGoogle Scholar
  12. 12.
    Wang J, D Ding and RJ Salvi (2002) Functional reorganization in chinchilla inferior colliculus associated with chronic and acute cochlear damage. Hear Res. 168:238–49.PubMedCrossRefGoogle Scholar
  13. 13.
    Syka J, N Rybalko and J Popelar (1994) Enhancement of the auditory cortex evoked responses in awake guinea pigs after noise exposure. Hear Res. 78:158–68.PubMedCrossRefGoogle Scholar
  14. 14.
    Syka J and J Popelar (1982) Noise impairment in the guinea pig. I. Changes in electrical evoked activity along the auditory pathway. Hear Res. 8:263–72.PubMedCrossRefGoogle Scholar
  15. 15.
    Gerken GM (1996) Central tinnitus and lateral inhibition: an auditory brainstem model. Hear Res. 97:75–83.PubMedGoogle Scholar
  16. 16.
    Caspary DM, A Raza, BA Lawhorn Armour et al (1990) Immunocytochemical and neurochemical evidence for age-related loss of GABA in the inferior colliculus: Implications for neural presbycusis. J Neurosci. 10:2363–72.PubMedGoogle Scholar
  17. 17.
    Salvi RJ and WA Ahroon (1983) Tinnitus and neural ­activity. J Speech Hear Res. 26:629–32.PubMedGoogle Scholar
  18. 18.
    Schaette R and R Kempter (2008) Development of hyperactivity after hearing loss in a computational model of the dorsal cochlear nucleus depends on neuron response type. Hear Res. 240:57–72.PubMedCrossRefGoogle Scholar
  19. 19.
    Szczepaniak WS and AR Møller (1995) Evidence of decreased GABAergic influence on temporal integration in the inferior colliculus following acute noise exposure: A study of evoked potentials in the rat. Neurosci Lett. 196:77–80.PubMedCrossRefGoogle Scholar
  20. 20.
    Szczepaniak WS and AR Møller (1996) Effects of (-)-baclofen, clonazepam, and diazepam on tone exposure-induced hyperexcitability of the inferior colliculus in the rat: possible therapeutic implications for pharmacological management of tinnitus and hyperacusis. Hear Res. 97:46–53.PubMedGoogle Scholar
  21. 21.
    Watanabe K, T Kamio, D Ohkawara et al (1977) Suppression of tinnitus by band noise masker–a study of 600 cases. Nippon Jibiinkoka Gakkai Kaiho. 100:900–6.Google Scholar
  22. 22.
    Souliere CJ, P Kileny, TA Zwolan et al (1992) Tinnitus suppression following cochlear implantation. A multifactorial investigation. Arch Otolaryngol Head Neck Surg. 118:1291–7.PubMedCrossRefGoogle Scholar
  23. 23.
    Kral A and V Majernik (1996) On lateral inhibition in the auditory system. Gen Physiol Biophys. 15:109–27.PubMedGoogle Scholar
  24. 24.
    Rubinstein JT, RS Tyler, A Johnson et al (2003) Electrical suppression of tinnitus with high-rate pulse trains. Otol Neurotol 24:478–85.PubMedCrossRefGoogle Scholar
  25. 25.
    Portmann M, Y Cazals, M Negrevergne et al (1979) Temporary. tinnitus suppression in many through electrcial stimulation of the cochlea. Acta Otolaryngol (Stockh). 87:249–99.CrossRefGoogle Scholar
  26. 26.
    Cazals Y, M Negrevergne and JM Aran (1978) Electrical stimulation of the cochlea in man: Hearing induction and tinnitus suppression. J Am Audiol Soc. 3:209–13.PubMedGoogle Scholar
  27. 27.
    Aran JM and I Cazals (1981) Electrical suppression of tinnitus, in Ciba Foundation Symposium 85. 1981, Pitman Books Ltd: London. 217–25.Google Scholar
  28. 28.
    Bartels H, MJ Staal and FW Albers (2007) Tinnitus and neural plasticity of the brain. Otol Neurotol. 28:178–84.PubMedCrossRefGoogle Scholar
  29. 29.
    Møller AR (2008) Neural Plasticity: For Good and Bad. Progress of Theoretical Physics Supplement No 173:48–65.Google Scholar
  30. 30.
    Rajan R (2001) Plasticity of excitation and inhibition in the receptive field of primary auditory cortical neurons after limited receptor organ damage. Cereb Cortex. 11:171–82.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.School of Behavioral and Brain SciencesThe University of Texas at DallasRichardsonUSA

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