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Biology of Stem Cells and the Molecular Basis of the Stem State pp 151–175Cite as

A Critical Analysis of Properties Commonly Ascribed to Stem Cells

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Part of the book series: Stem Cell Biology and Regenerative Medicine ((STEMCELL))

Abstract

Quiescence, self-renewal, asymmetric division, and niche dependence are important stem cell properties, but are not stem cell specific. Similarly, multipotency is often found in committed progenitor cells. By contrast, stem cells are unique in their pluripotency and relatively high plasticity. Pluripotent stem cells stand out, and profoundly differ from all other cells that exist in the organism. On the basis of these observations, an alternative definition of stemness is presented in the next chapter.

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  1. Department of Molecular Cell Biology, Weizmann Institute of Science, 76 100, Rehovot, Israel

    Dov Zipori

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Zipori, D. (2009). A Critical Analysis of Properties Commonly Ascribed to Stem Cells. In: Biology of Stem Cells and the Molecular Basis of the Stem State. Stem Cell Biology and Regenerative Medicine. Humana Press. https://doi.org/10.1007/978-1-60761-130-1_5

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