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Long Chain Polyunsaturated Fatty Acids: Immunomodulators in Disease

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Book cover Dietary Components and Immune Function

Part of the book series: Nutrition and Health ((NH))

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Key Points

(n-3) LCPUFA metabolites induce eicosanoid and docosanoid production, alter gene expression and modify lipid raft composition altering T-cell signaling all contribute to immunological functional changes. The interventional studies that have been performed for prevention of allergy, infectious and inflammatory diseases confirmed influence on T-cell function and cytokine profiles but clinical beneficial effects are more conflicting.

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Authors and Affiliations

  1. Clinique de Pédiatrie, CHRU de Lille, EA3925, IFR114, Faculté de Médecine, Université de Lille2, Lille, France

    Jean-Luc Desseyn PHD & Frédéric Gottrand MD, PHD

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  1. Jean-Luc Desseyn PHD
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  2. Frédéric Gottrand MD, PHD
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Editors and Affiliations

  1. Health Sciences Center, Department of Health Promotion Sciences, University of Arizona, 1295 N. Martin Ave. 1295, Tucson, 85724-5155, USA

    Ronald Ross Watson

  2. Mel & Enid Zuckerman College of, Public Health, University of Arizona, Tucson, 85724-5163, USA

    Sherma Zibadi

  3. Dept. Nutrition & Dietetics, King's College, Stamford St. 150, London, SE1 9NH, United Kingdom

    Victor R. Preedy

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Desseyn, JL., Gottrand, F. (2010). Long Chain Polyunsaturated Fatty Acids: Immunomodulators in Disease. In: Watson, R., Zibadi, S., Preedy, V. (eds) Dietary Components and Immune Function. Nutrition and Health. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60761-061-8_9

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  • DOI: https://doi.org/10.1007/978-1-60761-061-8_9

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