Abstract
Osteosarcoma is a primary malignant tumor of the skeleton characterized by its production of osteoid matrix. The classic osteosarcoma is rare, with an estimated incidence of two cases/million population/year in Japan. It is most common in males and occurs primarily in the second decade of life. Years ago patients with osteosarcoma were treated with surgical resection only, with more than 80 % of the patients ultimately dying of this disease. Today osteosarcoma is treated with pre- and postoperative chemotherapy plus surgery, and the percentage of patients cured varies between 60 and 70 % [1, 2].
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References
Picci P. Osteosarcoma (osteogenic sarcoma). Orphanet J Rare Dis. 2007;2:6.
Gebhardt MC, Hornicek FJ. Osteosarcoma. In: Menedenz LR, Âeditor. Orthopaedic knowledge update: musculoskeletal tumors. Rosemont, IL: American Academy of Orthopaedic Surgeons; 2002. p. 175–86.
Dickey ID, Rose PS, Fuchs B, et al. Dedifferentiated chondrosarcoma: the role of chemotherapy with updated outcomes. J Bone Joint Surg Am. 2004;86:2412–8.
Mitchell AD, Ayoub K, Mangham DC, Grimer RJ, Carter SR, Tillman RM. Experience in the treatment of dedifferentiated chondrosarcoma. J Bone Joint Surg Br. 2000;82:55–61.
Sakamoto A, Iwamoto Y. Current status and perspectives regarding the treatment of osteosarcoma: chemotherapy. Rev Recent Clin Trials. 2008;3:228–31.
Bielack SS, Carrle D. State-of-the-art approach in selective curable tumors: bone sarcoma. Ann Oncol. 2008;19 Suppl 7:vii155–60.
Gelderblom H, Hogendoorn PC, Dijkstra SD, et al. The clinical approach towards chondrosarcoma. Oncologist. 2008;13:320–9.
Brenner W, Bohuslavizki KH, Eary JF. PET imaging of osteosarcoma. J Nucl Med. 2003;44:930–42.
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Matsuda, S., Iwamoto, Y. (2013). Osteogenic Sarcoma and Dedifferentiated Chondrosarcoma Surveillance Counterpoint: Japan. In: Johnson, F., et al. Patient Surveillance After Cancer Treatment. Current Clinical Oncology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60327-969-7_47
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DOI: https://doi.org/10.1007/978-1-60327-969-7_47
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