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Sjögren’s Syndrome pp 415–421Cite as

New Approaches for the Management of Dry Mouth and Dry Eye in Sjogren’s Syndrome in Japan

Dry Eye Part

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Abstract

The first-line of treatment in the management of dry eye Sjogren’s syndrome patients is using artificial tears without preservatives and hyaluronic acid, which brings moisture to the ocular surface, preventing desiccation. However, recent findings suggest that dry eye is caused not only by the desiccation, but also by the lack of tear components. The second treatment regimen should include the supply of the tear components such as vitamin A and EGF to the ocular surface. The punctum plug is one choice of treatment when the patient has a minimal level of tear production. However, those patients who do not even produce even the smallest amount of tears, treatment by autologous serum eye drops becomes necessary. Serum has many components that exist in tears, so the 20% diluted autologous serum can be a good source of tear components for the ocular surface. In this chapter we focus on this tear component supply treatment.

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Authors and Affiliations

  1. Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan

    Kazuo Tsubota

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  1. Kazuo Tsubota
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Correspondence to Kazuo Tsubota .

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Editors and Affiliations

  1. Research Foundation, Rheumatology Clinic, Scripps Memorial Hospital &, Caminito Sinnecock 6565, La Jolla, 92037, California, USA

    Robert I. Fox

  2. Research Foundation, Rheumatology Clinic, Scripps Memorial Hospital &, Caminito Sinnecock 6565, La Jolla, 92037, California, USA

    Carla M. Fox

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Tsubota, K. (2011). New Approaches for the Management of Dry Mouth and Dry Eye in Sjogren’s Syndrome in Japan. In: Fox, R., Fox, C. (eds) Sjögren’s Syndrome. Springer, New York, NY. https://doi.org/10.1007/978-1-60327-957-4_24

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  • DOI: https://doi.org/10.1007/978-1-60327-957-4_24

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  • Print ISBN: 978-1-60327-956-7

  • Online ISBN: 978-1-60327-957-4

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