Skip to main content

Use of Multislice CT and MRI for the Evaluation of Patients with Chest Pain

  • Chapter
  • First Online:
Book cover Short Stay Management of Chest Pain

Part of the book series: Contemporary Cardiology ((CONCARD))

  • 744 Accesses

Abstract

Approximately 6 million patients are evaluated annually in United States emergency departments for acute chest pain (McCaig and Burt, National Hospital Ambulatory Medical Care Survey 2003. National Center for Health Statistics: Hyattsville, MD, 2005). Delineation of the presence or absence of an acute coronary syndrome must be accurate and efficient. The latest estimate is that 2% of patients with an acute coronary syndrome are inappropriately sent home from the emergency department (Pope et al. N Engl J Med 2000;342:1163–1170; Lee and Goldman, N Engl J Med 2000;342:1163–1170). These patients suffer higher morbidity than admitted patients. Missed ACS was the number one payout per case and that accounts for 41% of claims paid. So not surprisingly physicians do not want to miss ACS, resulting in an annual cost of US$10 to $13 billion to rule out ACS (McCaig and Burt, The National Hospital Ambulatory Medical Care Survey. Centers for Disease Control and Prevention’s National Center for Health Statistics, 2005).

Coronary CT angiography (CCTA) has great promise as a tool to expedite the triage of acute chest pain patients. The direct visualization of the coronary anatomy, the ability to simultaneously image the rest of the thorax to exclude aortic dissection and pulmonary embolism and the ability to provide alternate causes of chest pain, such as pneumonia, pericardial fluid, and esophageal inflammation. This chapter will examine the use of coronary CT angiography and MRI for the evaluation of acute chest pain.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. McCaig LF, Burt CW, National Hospital Ambulatory Medical Care Survey 2003: Emergency Department Summary: Advance Data from Vital and Health Statistics, No. 358. Hyattsville, MD: National Center for Health Statistics; 2005.

    Google Scholar 

  2. Pope JH, Aufderhelde TP, Ruthazer R, et al. Missed diagnoses of acute cardiac ischemia in the emergency department. N Engl J Med 2000;342:1163–1170.

    Article  PubMed  CAS  Google Scholar 

  3. Lee TH, Goldman L. Evaluation of the patient with acute chest pain. N Engl J Med 2000; 342:1187–1195.

    Article  PubMed  CAS  Google Scholar 

  4. Lee TH, Rouan GW, Weisberg MC, et al. Clinical characteristics and natural history of patients with acute myocardial infarction sent home from the emergency room. Am J Cardiol 1987;60:219–224.

    Article  PubMed  CAS  Google Scholar 

  5. Karcz A, Korn R, Burke MC, et al. Malpractice claims against emergency physicians in Massachusetts: 1975–1993. Am J Emerg Med. 1996;14:341–345.

    Article  PubMed  CAS  Google Scholar 

  6. Kalendar WA, Seissler W, Klotz E, Vock P. Spiral volumetric CT with single breath-hold technique: continuous transport and continuous scanner rotation. Radiology 1990;176:181–183.

    Google Scholar 

  7. Ohnesorge B, Flohr T, Becker C, et al. Cardiac imaging by means of electrocardiographically gated multisection spiral CT: initial experience. Radiology 2000;217:564–571.

    PubMed  CAS  Google Scholar 

  8. Achenbach S, Ulzheimer S, Baum U, et al. Noninvasive coronary angiography by retrospectively ECG-gated multislice spiral CT. Circulation 2000;102:2823–2828.

    PubMed  CAS  Google Scholar 

  9. Raff GL, Gallagher MJ, O’Neill WW, et al. Diagnostic accuracy of noninvasive coronary angiography using 64-slice spiral computed tomography. J Am Coll Cardiol 2005;46:552–557.

    Article  PubMed  Google Scholar 

  10. Mollet NR, Cademartiri F, van Mieghem CA, et al. High-resolution spiral computed tomography coronary angiography in patients referred for diagnostic conventional angiography. Circulation 2005;112:2318–2323.

    Article  PubMed  Google Scholar 

  11. Leber AW, Knez A, von Ziegler F, et al. Quantification of obstructive and nonobstructive coronary lesions by 64-slice computed tomography. J Am Coll Cardiol 2005;46:147–154.

    Article  PubMed  Google Scholar 

  12. Sato Y, Matsumoto N, Ichikawa M, et al. Efficacy of multislice computed tomography for the detection of acute coronary syndrome in the emergency department. Circ J 2005:69:1047–1051.

    Article  PubMed  Google Scholar 

  13. White CS, Kuo D, Kelemen M, et al. Chest pain evaluation in the emergency department: Can MDCT provide a comprehensive evaluation? AJR 2005;185:533–540.

    PubMed  Google Scholar 

  14. Hoffmann U, Nagurney JT, Moselewski F, et al. Coronary multidetector computed tomography in the assessment of patients with acute chest pain. Circulation 2006;114:2251–2260.

    Article  PubMed  Google Scholar 

  15. Gallagher MJ, Ross MA, Raff GL, et al. The diagnostic accuracy of 64-slice computed tomography coronary angiography compared with stress nuclear imaging in emergency department low-risk chest pain patients. Ann Emerg Med 2007;49:125–136.

    Article  PubMed  Google Scholar 

  16. Rubinshtein R, Halon DA, Gaspar T, et al. Usefulness of 64-slice cardiac computed tomographic angiography for diagnosing acute coronary syndromes and predicting clinical outcome in emergency department patients with chest pain of uncertain origin. Circulation 2007;115:1762–1768.

    Article  PubMed  Google Scholar 

  17. Goldstein JA, Gallagher MJ, O’Neill WW, et al. A randomized controlled trial of multi-slice coronary computed tomography for evaluation of acute chest pain patients. J Am Coll Cardiol 2007;49:863–871.

    Article  PubMed  Google Scholar 

  18. Willoteaux S, Lions C, Gaxotte V, et al. Imaging of aortic dissection by helical computed tomography (CT). Eur Radiol 2004;14:1999–2008.

    Article  PubMed  Google Scholar 

  19. Yoshida S, Akiba H, Tamakawa M, et al. Thoracic involvement of type A aortic dissection and intramural hematoma: diagnostic accuracy – comparison of emergency helical CT and surgical findings. Radiology 2003;228: 430–435.

    Article  PubMed  Google Scholar 

  20. Hamada S, Takamiya M, Kimura K, et al. Type A aortic dissection: evaluation with ultrafast CT. Radiology 1992;183:155–158.

    PubMed  CAS  Google Scholar 

  21. Sebastia C, Pallisa E, Quiroga S, et al. Aortic dissection: diagnosis and follow-up with helical CT. RadioGraphics 1999;19:45–60.

    PubMed  CAS  Google Scholar 

  22. Shiga T, Wajima Z, Apfel CC, et al. Diagnostic accuracy of transesophageal echocardiography, helical computed tomography, and magnetic resonance imaging for suspected thoracic aortic dissection. Arch Intern Med 2006;166:1350–1356.

    Article  PubMed  Google Scholar 

  23. Ghaye B, Remy J, Remy-Jardin M. Non-traumatic thoracic emergencies: CT diagnosis of acute pulmonary embolism: the first 10 years. Eur Radiol 2002;12:1886–1905.

    PubMed  Google Scholar 

  24. Anderson DR, Kovacs MJ, Dennie C, et al. Use of spiral computed tomography contrast angiography and ultrasonography to exclude the diagnosis of pulmonary embolism in the emergency department. J Emerg Med 2005;29:399–404.

    Article  PubMed  Google Scholar 

  25. Prologo JD, Gilkeson RC, Diaz M, et al. CT pulmonary angiography: a comparative analysis of the utilization patterns in emergency department and hospitalized patients between 1998 and 2003. Am J Roentgenol 2004;183:1093–1096.

    Google Scholar 

  26. Ghanima W, Almaas V, Aballi S, et al. Management of suspected pulmonary embolism (PE) by D-dimer and multi-slice computed tomography in outpatients: an outcome study. J Thromb Haemost 2005;3:1926–1932.

    Article  PubMed  CAS  Google Scholar 

  27. Quiroz R, Kucher N, Zou KH. Clinical validity of a negative computed tomography scan in patients with suspected pulmonary embolism: a systematic review. JAMA 2005;293:2012–2017.

    Article  PubMed  CAS  Google Scholar 

  28. Vrachliotis TG, Bis KG, Haidary A, et al. Atypical chest pain: coronary, aortic, and pulmonary vasculature enhancement at biphasic single-injection 64-section CT angiography. Radiology 2007;243:Number 2:368–376.

    Article  PubMed  Google Scholar 

  29. Onuma K, Tanabe, Nakazawa G, et al. Noncardiac findings in cardiac imaging with multidetector computed tomography. J Am Coll Cardiol 2006;48:402–406.

    Article  PubMed  Google Scholar 

  30. Leschka S, Alkadhi H, Plass A, et al. Accuracy of MSCT coronary angiography with 64-slice technology: first experience. Eur Heart J 2005;26:1482–1487.

    Article  PubMed  Google Scholar 

  31. Pugliese F, Mollet NR, Runza G, et al. Diagnostic accuracy of non-invasive 64-slice CT coronary angiography in patients with s angina pectoris. Eur Radiol 2006;16:575–582.

    Article  PubMed  Google Scholar 

  32. Ropers D, Rixe J, Anders K, et al. Usefulness of multidetector row spiral computed tomography with 64- × 0.6-mm collimation and 330-ms rotation for the noninvasive detection of significant coronary artery stenoses. Am J Cardiol 2006;97:343–348.

    Article  PubMed  Google Scholar 

  33. Hamon M, Biondi-Zoccai GGL, Malagutti P, Agostoni P, Morello R, Valgimigli M, Hamon M. Diagnostic performance of multislice spiral computed tomography of coronary arteries as compared with conventional invasive coronary angiography: A meta analysis. J Am Coll Cardiol 2006;48:1896–1910.

    Article  PubMed  Google Scholar 

  34. Raff GL, Goldstein JA. Coronary angiography by computed tomography: coronary imaging evolves. J Am Coll Cardiol 2007;49:1830–1833.

    Article  PubMed  Google Scholar 

  35. Raff GL, O'Neill WW, Gentry RE, Dulli A, Bis KG, Shetty AN, Goldstein JA. Microvascular Obstruction and Myocardial Function after Acute Myocardial Infarction: assessment by Using Contrast-enhanced Cine MR Imaging. Radiology 2006;240(2): 629–838.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Brian O’Neil .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2009 Humana Press, a part of Springer Science+Business Media, LLC

About this chapter

Cite this chapter

O’Neil, B., Gallagher, M.J., Raff, G.L. (2009). Use of Multislice CT and MRI for the Evaluation of Patients with Chest Pain. In: Cannon, C., Peacock, W. (eds) Short Stay Management of Chest Pain. Contemporary Cardiology. Humana Press. https://doi.org/10.1007/978-1-60327-948-2_13

Download citation

  • DOI: https://doi.org/10.1007/978-1-60327-948-2_13

  • Published:

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-60327-947-5

  • Online ISBN: 978-1-60327-948-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics