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Hospital Infection Control: Considerations for the Management and Control of Drug-Resistant Organisms

  • Chapter
Antimicrobial Drug Resistance

Part of the book series: Infectious Disease ((ID))

  • 2011 Accesses

The prevalence of nosocomially acquired, antibiotic–resistant organisms has increased signifi cantly over the last 20 years. Data from the National Nosocomial Infections Surveillance (NNIS) system report published in 2000 revealed an alarming proportion of drug–resistant pathogens (1). The NNIS system data comprise a nonrandom sample of 290 hospitals from 42 states. Monthly reports of nosocomial infections and microbiology data from participating institutions are analyzed. From the sample, in 2000, 52% of all Staphylococcus aureus isolates were resistant to methicillin, 25% of enterococci were vancomycin resistant, and 88% of coagulase negative staphylococci were methicillin resistant (1). An increase in drug-resistant staphylococci and enterococci has also been reported in Europe and South America (2–4).

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  1. Department of Medicine, Virginia Commonwealth University Medical Center, Richmond, VA, USA

    Gonzalo M. L. Bearman & Richard P. Wenzel (William Branch Porter Professor and Chair)

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  1. Executive Vice President & Chief Medical Officer, Idenix Pharmaceuticals, Cambridge, MA, USA

    Douglas L. Mayers MD

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Bearman, G.M.L., Wenzel, R.P. (2009). Hospital Infection Control: Considerations for the Management and Control of Drug-Resistant Organisms. In: Mayers, D.L. (eds) Antimicrobial Drug Resistance. Infectious Disease. Humana Press. https://doi.org/10.1007/978-1-60327-595-8_42

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