The Peripheral Nerve and Cutaneous Neural Tumors: Introduction, Definitions, and Classification

  • Zsolt ArgenyiEmail author
  • Chris H. Jokinen
Part of the Current Clinical Pathology book series (CCPATH)


Peripheral nerves, brain, and spinal cord comprise the neural organ system, which is traditionally divided by its components into the peripheral nervous system and central nervous system. Cutaneous peripheral nerves are responsible for the transmission of sensory information, motor function, and control of multiple functions vital to preservation of the integument and survival of the human. Among these are sensory of the external environment through touch and pressure, and temperature regulation by control over erector pili muscle, eccrine duct secretion for sweating, and constriction or dilation of blood vessels for conservation or release of heat. The peripheral component of the neural organ system includes nerve fibers, nerve fascicles, and various sensory receptors.


Classifications Terminology Normal histology Histogenesis Ultrastructure Normal peripheral nerve 

Additional Reading

  1. Eames RA, Gamble HJ. Schwann cell relationships in normal human cutaneous nerves. J Anat. 1970;106:417.PubMedGoogle Scholar
  2. Gamble HJ, Eames RA. An electron microscope study of the connective tissues of human peripheral nerve. J Anat. 1964;98:655.PubMedGoogle Scholar
  3. Reed ML, Jacoby RA. Cutaneous neuroanatomy and neuropathology. Normal nerves, neural-crest derivatives, and benign neural neoplasms in the skin. Am J Dermatopathol. 1983;5:335.CrossRefPubMedGoogle Scholar
  4. Sternberg S. Histology for pathologists. 2nd ed. Philadelphia, PA: Lippincott Williams & Wilkins; 1997.Google Scholar

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.SeattleUSA
  2. 2.Department of PathologyEssentia Health, Duluth ClinicDuluthUSA

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