Abstract
Although endocrine causes of erectile dysfunction (ED) have been well recognized for decades, historically there has been little emphasis on endocrine evaluation or treatment for men with ED. Endocrine abnormalities as a cause or contributing factor for ED are important to recognize since these may be associated with significant additional medical problems, and also because correction of the endocrinopathy often leads to improvement or resolution of ED.
This chapter reviews the endocrine causes of ED, and provides a practical approach to the endocrine evaluation and treatment of men with ED. A major emphasis of this chapter is related to testosterone deficiency, which may contribute to ED at various levels, including the brain, peripheral nerves, vasculature, and penis. Testosterone deficiency is becoming increasingly recognized as an important health issue for aging men, with a high prevalence among the age groups at risk for development of ED. Testosterone therapy in these men may resolve ED completely, or may allow for greater responsiveness to more traditional therapies, such as the oral phosphodiesterase 5 inhibitors. A basic hormonal evaluation should be considered for all men presenting with sexual dysfunction.
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Moreno, S.A., Morgentaler, A. (2011). Hormonal Evaluation and Therapy in Erectile Dysfunction. In: McVary, K. (eds) Contemporary Treatment of Erectile Dysfunction. Contemporary Endocrinology. Humana Press. https://doi.org/10.1007/978-1-60327-536-1_12
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