Cytotoxic Chemotherapy and Endocrine Therapy for Hepatocellular Carcinoma

  • Daniel Palmer
  • Philip J. Johnson


For the minority of patients with hepatocellular carcinoma (HCC), surgical therapy, including transplantation, or local ablation may offer the prospect of cure (see Chapters 9–17). However, these treatments are typically constrained by size and/or number of tumours as well as liver dysfunction and other comorbidities.


Cytotoxic chemotherapy Endocrine therapy Doxorubicin Tamoxifen Somatostatin analogues Drug resistance 


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Daniel Palmer
    • 1
  • Philip J. Johnson
    • 1
  1. 1.Clinical Trials Unit, CRUK Institute for Cancer StudiesUniversity of BirminghamBirminghamUK

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