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Radiofrequency Ablation for Eradication of Barrett’s Esophagus: A Description of the Endoscopic Technique, Its Clinical Results, and Future Prospects

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Endoscopic Therapy for Barrett's Esophagus

Part of the book series: Clinical Gastroenterology ((CG))

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Summary

Stepwise circumferential and focal radiofrequency ablation using the HALO system is a novel and promising ablative modality for Barrett’s esophagus. Primary circumferential ablation is performed using a balloon-based bipolar electrode, while secondary treatment of residual Barrett’s epithelium is performed using an endoscope-mounted bipolar electrode on an articulated platform. Recent studies suggest that this ablation technique is highly effective in removing Barrett’s mucosa and its associated dysplasia without the known drawbacks of photodynamic therapy or argon plasma coagulation such as esophageal stenosis and subsquamous foci of columnar epithelium (a.k.a. “buried Barrett”). In this review chapter we will explain the technical background of radiofrequency ablation using the HALO system, give a summary of its current status, and speculate on possible future applications.

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Authors and Affiliations

  1. Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands

    Roos E. Pouw MD & Jacques J.G.H.M. Bergman MD, PhD

Authors
  1. Roos E. Pouw MD
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  2. Jacques J.G.H.M. Bergman MD, PhD
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Editors and Affiliations

  1. College of Medicine, University of Arizona, Tucson, 85724-5028, U.S.A.

    Richard E. Sampliner

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© 2009 Humana Press, a part of Springer Science+Business Media, LLC

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Pouw, R.E., Bergman, J.J. (2009). Radiofrequency Ablation for Eradication of Barrett’s Esophagus: A Description of the Endoscopic Technique, Its Clinical Results, and Future Prospects. In: Sampliner, R. (eds) Endoscopic Therapy for Barrett's Esophagus. Clinical Gastroenterology. Humana Press. https://doi.org/10.1007/978-1-60327-445-6_3

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  • DOI: https://doi.org/10.1007/978-1-60327-445-6_3

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  • Publisher Name: Humana Press

  • Print ISBN: 978-1-60327-444-9

  • Online ISBN: 978-1-60327-445-6

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