Abstract
Holmes’ tremor, also known as thalamic, midbrain, or rubral tremor, is characterized by a combination of irregular resting, postural, and intention tremors of large amplitude and slow frequency of less than 4.5 Hz. The tremor predominantly affects the proximal upper extremities unilaterally and is often markedly activated by goal-directed movements. Etiology is usually a structural lesion of the brainstem, cerebellum, or thalamus as a result of stroke, vascular malformation, tumor, multiple sclerosis, trauma, or infection. There may be a variable delay of 2 weeks to 2 years between the precipitating event and the initial appearance of tremor.
This chapter contains a video segment which can be found at the URL: https://doi.org/10.1007/978-1-60327-426-5_27
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Deuschl G, Bain P, Brin M, et al. Consensus statement of the Movement Disorder Society on tremor. Mov Disord. 1998;13 Suppl 3:2–23.
Gajos GA, Bogucki A, Schinwelski M, et al. The clinical and neuroimaging studies in Holmes tremor. Acta Neurol Scand. 2010;122:360–6.
Paviour DC, Jager HR, Wilkinson L, et al. Holmes’ tremor: application of modern neuroimaging technique. Mov Disord. 2006;21:2260–2.
Author information
Authors and Affiliations
Electronic Supplementary material
Holmes midbrain tremor.mp4 (MP4 5,548KB)
Clip 1: the patient exhibits severe postural tremor of the left arm. Not shown are equally severe resting and kinetic tremor. Clip 2: the patient attempts goal-directed arm movements but is unable to carry them out (Video contribution from Dr. Parnsiri Chairangsaris, Pramongkutklao Hospital, Thailand).
Rights and permissions
Copyright information
© 2012 Springer Science+Business Media New York
About this chapter
Cite this chapter
Bhidayasiri, R., Tarsy, D. (2012). Holmes’ Midbrain Tremor. In: Movement Disorders: A Video Atlas. Current Clinical Neurology. Humana, Totowa, NJ. https://doi.org/10.1007/978-1-60327-426-5_27
Download citation
DOI: https://doi.org/10.1007/978-1-60327-426-5_27
Published:
Publisher Name: Humana, Totowa, NJ
Print ISBN: 978-1-60327-425-8
Online ISBN: 978-1-60327-426-5
eBook Packages: MedicineMedicine (R0)