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Tumors of Thyroid Gland: Non-C cell Tumors

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Surgical Pathology of Endocrine and Neuroendocrine Tumors

Part of the book series: Current Clinical Pathology ((CCPATH))

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Abstract

Thyroid tumors are one of the most common tumors of the endocrine system encountered in surgical pathology practice. They can arise from the follicular lining epithelial cells that produce the thyroid hormone or the C cells that secrete calcitonin. In this chapter we discuss non-C cell tumors of the thyroid. In this group of tumors papillary carcinoma is the most common malignancy and the conventional type of tumor can be easily diagnosed based on classical cytomorphologic features. However, variants of papillary carcinoma exist, the understanding of which is crucial for accurate diagnoses. The follicular patterned tumors may sometimes pose diagnostic challenge and approach to these thyroid lesions is suggested in this section along with ancillary studies that may help in the diagnosis of these tumors. Finally, thyroid cancer progression from differentiated carcinoma to poorly differentiated and anaplastic carcinoma is well known and is also presented along with clinical and pathological correlations.

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Authors and Affiliations

  1. Department of Pathology, University of Massachusetts Medical School, UMassMemorial Medical Center, Three Biotech, One Innovation Drive, Worcester, MA 01605, USA

    Ashraf Khan (Professor of Patholog, Director, Surgical Pathology) & Manju Prasad (Associate Professor of Pathology Director Immunohistochemistry)

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  1. Ashraf Khan
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  2. Manju Prasad
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Correspondence to Ashraf Khan .

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  1. School (UMMS), University of Massachusetts Medical, Lake Avenue N. 55, Worcester, 01655, U.S.A.

    Ashraf Khan

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Khan, A., Prasad, M. (2009). Tumors of Thyroid Gland: Non-C cell Tumors. In: Khan, A. (eds) Surgical Pathology of Endocrine and Neuroendocrine Tumors. Current Clinical Pathology. Humana Press. https://doi.org/10.1007/978-1-60327-396-1_5

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  • DOI: https://doi.org/10.1007/978-1-60327-396-1_5

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