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Surgical Pathology of Endocrine and Neuroendocrine Tumors pp 131–142Cite as

Endocrine Tumors of the Lung and Upper Airways

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Part of the book series: Current Clinical Pathology ((CCPATH))

Abstract

Neuroendocrine tumors stand alone among other members of the larger family of tumors of the lung and upper airways. While relatively uncommon, they have, over the years, been the subject of considerable attention and study. A recent search of the literature yielded thousands of citations for small cell carcinoma, a single entity within the spectrum of neuroendocrine tumors. This chapter discusses the intriguing putative role of neuroendocrine cell hyperplasia as a possible precursor of these tumors. In addition, this chapter explores the similarities as well as differences between neuroendocrine and non-neuroendocrine tumors. Lastly, this chapter attempts to provide concise up-to-date information on both current, consensus –based morphologic criteria and the application of modern techniques, particularly immunohistochemical techniques that may facilitate histopathological diagnosis.

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Authors and Affiliations

  1. University of Massachusetts Medical School, UMassMemorial Medical Center, Three Biotech, One Innovation Drive, Worcester, MA, USA

    Armando E. Fraire (Professor of Pathology, Director, Pulmonary and Autopsy Pathology)

  2. Institute of Pathology Teaching Hospital Feldkirch Carinagasse, 47, A-6800 Feldkirch, Austria

    Ulrike M. Gruber-Mösenbacher

  3. Institute of Pathology, Research Unit Molecular Lung and Pleura Pathology, Lab. Molecular Genetics,Environmental und Respiratory Pathology, Medical University of Graz, Auenbruggerplatz 25,A-8036, Graz, Austria

    Helmut H. Popper (MD,Prof.Path)

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  1. Armando E. Fraire
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  2. Ulrike M. Gruber-Mösenbacher
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  3. Helmut H. Popper
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Correspondence to Armando E. Fraire .

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Editors and Affiliations

  1. School (UMMS), University of Massachusetts Medical, Lake Avenue N. 55, Worcester, 01655, U.S.A.

    Ashraf Khan

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Fraire, A.E., Gruber-Mösenbacher, U.M., Popper, H.H. (2009). Endocrine Tumors of the Lung and Upper Airways. In: Khan, A. (eds) Surgical Pathology of Endocrine and Neuroendocrine Tumors. Current Clinical Pathology. Humana Press. https://doi.org/10.1007/978-1-60327-396-1_10

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  • DOI: https://doi.org/10.1007/978-1-60327-396-1_10

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