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Essentials of Apoptosis pp 355–373Cite as

Programmed Cell Death in C. elegans

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Abstract

Studies in the nematode Caenorhabditis elegans have established that programmed cell death is a genetically determined part of development and is controlled by a specific set of genes. These genes have been ordered into a pathway through genetic analyses. This cell death pathway is evolutionarily conserved and provides a basis for understanding programmed cell death in more complex organisms, including humans. This chapter discusses the activation, cell killing, and engulfment processes in the model organism C. elegans.

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Authors and Affiliations

  1. Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO 80309-0347, USA

    Monica Darland-Ransom

  2. Department of Zoology, National Taiwan University, Taipei 10617, Taiwan

    Yi-Chun Wu

  3. Department of MCD Biology, University of Colorado, Boulder, CO 80309, USA

    Ding Xue

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  1. Monica Darland-Ransom
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  2. Yi-Chun Wu
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  3. Ding Xue
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Correspondence to Ding Xue .

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    © 2009 Humana Press, a part of Springer Science+Business Media, LLC

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    Darland-Ransom, M., Wu, YC., Xue, D. (2009). Programmed Cell Death in C. elegans . In: Dong, Z., Yin, XM. (eds) Essentials of Apoptosis. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60327-381-7_15

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