Skip to main content
SpringerLink
Log in

Sleep and Quality of Life in Renal Disease

  • Chapter
Sleep and Quality of Life in Clinical Medicine

Summary

Chronic kidney disease (CKD) leading to renal insufficiency and failure is a growing health care problem. It is well established that patients with end-stage renal disease (ESRD) have a diminished quality of life (QOL), as well as increased sleep complaints. Much less is known about individuals with early-stage CKD who do not require dialysis. Sleep disturbance appears to be part of the uremic syndrome, and manifests as excessive daytime sleepiness, changes in sleep architecture, sleep-disordered breathing/sleep apnea, and periodic limb movements (PLMs)/restless legs syndrome. Numerous studies in patients with ESRD have associated sleep disturbances with poor QOL, but very limited data exist on pre-dialysis CKD patients. There is increasing evidence that correction of uremia by intensification of dialysis or renal transplantation can improve sleep disturbances, as well as perceived QOL. These and other treatments for sleep disorders used in the general population require further research to demonstrate efficacy and the impact on QOL in patients with all stages of CKD.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Coresh J, Astor BC, Greene T, Eknoyan G, Levey AS. Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey. Am J Kidney Dis 2003; 41(1):1–12.

    Article  PubMed  Google Scholar 

  2. The United States Renal Data System (USRDS) 2005 Annual Report, Bethesda, MD, National Institutes of Health. 2005. National Institute of Diabetes and Digestive and Kidney Diseases.

    Google Scholar 

  3. Collins AJ, Li S, Ma JZ, Herzog C. Cardiovascular disease in end-stage renal disease patients. Am J Kidney Dis 2001; 38(4 Suppl 1):S26–S29.

    Google Scholar 

  4. Coresh J, Longenecker JC, Miller ER, III, Young HJ, Klag MJ. Epidemiology of cardiovascular risk factors in chronic renal disease. J Am Soc Nephrol 1998; 9(12 Suppl):S24–S30.

    PubMed  CAS  Google Scholar 

  5. Foley RN, Parfrey PS, Sarnak MJ. Clinical epidemiology of cardiovascular disease in chronic renal disease. Am J Kidney Dis 1998; 32(5 Suppl 3):S112–S119.

    PubMed  CAS  Google Scholar 

  6. Sarnak MJ, Jaber BL. Mortality caused by sepsis in patients with end-stage renal disease compared with the general population. Kidney Int 2000; 58(4):1758–1764.

    Article  PubMed  CAS  Google Scholar 

  7. Hakim RM, Breyer J, Ismail N, Schulman G. Effects of dose of dialysis on morbidity and mortality. Am J Kidney Dis 1994; 23(5):661–669.

    PubMed  CAS  Google Scholar 

  8. Held PJ, Port FK, Wolfe RA, Stannard DC, Carroll CE, Daugirdas JT, et al. The dose of hemodialysis and patient mortality. Kidney Int 1996; 50(2):550–556.

    Article  PubMed  CAS  Google Scholar 

  9. Owen WF, Jr., Lew NL, Liu Y, Lowrie EG, Lazarus JM. The urea reduction ratio and serum albumin concentration as predictors of mortality in patients undergoing hemodialysis. N Engl J Med 1993; 329(14):1001–1006.

    Article  PubMed  Google Scholar 

  10. Block GA, Klassen PS, Lazarus JM, Ofsthun N, Lowrie EG, Chertow GM. Mineral metabolism, mortality, and morbidity in maintenance hemodialysis. J Am Soc Nephrol 2004; 15(8):2208–2218.

    Article  PubMed  CAS  Google Scholar 

  11. Besarab A, Bolton WK, Browne JK, Egrie JC, Nissenson AR, Okamoto DM, et al. The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin. N Engl J Med 1998; 339(9):584–590.

    Article  PubMed  CAS  Google Scholar 

  12. Drueke TB, Locatelli F, Clyne N, Eckardt KU, Macdougall IC, Tsakiris D, et al. Normalization of hemoglobin level in patients with chronic kidney disease and anemia. N Engl J Med 2006; 355(20):2071–2084.

    Article  PubMed  CAS  Google Scholar 

  13. Singh AK, Szczech L, Tang KL, Barnhart H, Sapp S, Wolfson M, et al. Correction of anemia with epoetin alfa in chronic kidney disease. N Engl J Med 2006; 355(20): 2085–2098.

    Article  PubMed  CAS  Google Scholar 

  14. Eknoyan G, Beck GJ, Cheung AK, Daugirdas JT, Greene T, Kusek JW, et al. Effect of dialysis dose and membrane flux in maintenance hemodialysis. N Engl J Med 2002; 347(25):2010–2019.

    Article  PubMed  Google Scholar 

  15. Kimmel PL, Patel SS. Quality of life in patients with chronic kidney disease: focus on end-stage renal disease treated with hemodialysis. Semin Nephrol 2006; 26(1):68–79.

    Article  PubMed  Google Scholar 

  16. Bremer BA, McCauley CR, Wrona RM, Johnson JP. Quality of life in end-stage renal disease: a reexamination. Am J Kidney Dis 1989; 13(3):200–209.

    PubMed  CAS  Google Scholar 

  17. Carmichael P, Popoola J, John I, Stevens PE, Carmichael AR. Assessment of quality of life in a single centre dialysis population using the KDQOL-SF questionnaire. Qual Life Res 2000; 9(2):195–205.

    Article  PubMed  CAS  Google Scholar 

  18. Evans RW, Manninen DL, Garrison LP, Jr., Hart LG, Blagg CR, Gutman RA, et al. The quality of life of patients with end-stage renal disease. N Engl J Med 1985; 312(9):553–559.

    Article  PubMed  CAS  Google Scholar 

  19. Wolfe RA, Ashby VB, Milford EL, Ojo AO, Ettenger RE, Agodoa LY, et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med 1999; 341(23): 1725–1730.

    Article  PubMed  CAS  Google Scholar 

  20. Chang VT, Thaler HT, Polyak TA, Kornblith AB, Lepore JM, Portenoy RK. Quality of life and survival: the role of multidimensional symptom assessment. Cancer 1998; 83(1):173–179.

    Article  PubMed  CAS  Google Scholar 

  21. Gijsen R, Hoeymans N, Schellevis FG, Ruwaard D, Satariano WA, van den Bos GA. Causes and consequences of co-morbidity: a review. J Clin Epidemiol 2001; 54(7):661–674.

    Article  PubMed  CAS  Google Scholar 

  22. Peters R. Quality-of-life measures as predictors of mortality and morbidity. Curr Hypertens Rep 2001; 3(6):458–461.

    Article  PubMed  CAS  Google Scholar 

  23. Squier HC, Ries AL, Kaplan RM, Prewitt LM, Smith CM, Kriett JM, et al. Quality of well-being predicts survival in lung transplantation candidates. Am J Respir Crit Care Med 1995; 152(6 Pt 1):2032–2036.

    PubMed  CAS  Google Scholar 

  24. Wisloff F, Hjorth M. Health-related quality of life assessed before and during chemotherapy predicts for survival in multiple myeloma. Nordic Myeloma Study Group. Br J Haematol 1997; 97(1):29–37.

    Google Scholar 

  25. McClellan WM, Anson C, Birkeli K, Tuttle E. Functional status and quality of life: predictors of early mortality among patients entering treatment for end stage renal disease. J Clin Epidemiol 1991; 44(1):83–89.

    Article  PubMed  CAS  Google Scholar 

  26. Kimmel PL, Peterson RA, Weihs KL, Simmens SJ, Alleyne S, Cruz I, et al. Psychosocial factors, behavioral compliance and survival in urban hemodialysis patients. Kidney Int 1998; 54(1):245–254.

    Article  PubMed  CAS  Google Scholar 

  27. Kimmel PL. Psychosocial factors in dialysis patients. Kidney Int 2001; 59(4):1599–1613.

    Article  PubMed  CAS  Google Scholar 

  28. Devins GM, Mann J, Mandin H, Paul LC, Hons RB, Burgess ED, et al. Psychosocial predictors of survival in end-stage renal disease. J Nerv Ment Dis 1990; 178(2):127–133.

    Article  PubMed  CAS  Google Scholar 

  29. Kimmel PL, Weihs K, Peterson RA. Survival in hemodialysis patients: the role of depression. J Am Soc Nephrol 1993; 4(1):12–27.

    PubMed  CAS  Google Scholar 

  30. Peterson RA, Kimmel PL, Sacks CR, Mesquita ML, Simmens SJ, Reiss D. Depression, perception of illness and mortality in patients with end-stage renal disease. Int J Psychiatry Med 1991; 21(4):343–354.

    Article  PubMed  CAS  Google Scholar 

  31. Creagan ET. Attitude and disposition: do they make a difference in cancer survival? Mayo Clin Proc 1997; 72(2):160–164.

    Google Scholar 

  32. Eriksen W. The role of social support in the pathogenesis of coronary heart disease. A literature review. Fam Pract 1994; 11(2):201–209.

    Article  PubMed  CAS  Google Scholar 

  33. Seeman TE. Health promoting effects of friends and family on health outcomes in older adults. Am J Health Promot 2000; 14(6):362–370.

    PubMed  CAS  Google Scholar 

  34. Berkman LF. The role of social relations in health promotion. Psychosom Med 1995; 57(3):245–254.

    PubMed  CAS  Google Scholar 

  35. Holley JL, Nespor S, Rault R. A comparison of reported sleep disorders in patients on chronic hemodialysis and continuous peritoneal dialysis. Am J Kidney Dis 1992; 19(2):156–161.

    PubMed  CAS  Google Scholar 

  36. Walker S, Fine A, Kryger MH. Sleep complaints are common in a dialysis unit. Am J Kidney Dis 1995; 26(5):751–756.

    PubMed  CAS  Google Scholar 

  37. Williams SW, Tell GS, Zheng B, Shumaker S, Rocco MV, Sevick MA. Correlates of sleep behavior among hemodialysis patients. The kidney outcomes prediction and evaluation (KOPE) study. Am J Nephrol 2002; 22(1):18–28.

    Google Scholar 

  38. Iliescu EA, Yeates KE, Holland DC. Quality of sleep in patients with chronic kidney disease. Nephrol Dial Transplant 2004; 19(1):95–99.

    Article  PubMed  Google Scholar 

  39. Novak M, Shapiro CM, Mendelssohn D, Mucsi I. Diagnosis and management of insomnia in dialysis patients. Semin Dial 2006; 19(1):25–31.

    Article  PubMed  Google Scholar 

  40. Millman RP, Kimmel PL, Shore ET, Wasserstein AG. Sleep apnea in hemodialysis patients: the lack of testosterone effect on its pathogenesis. Nephron 1985; 40(4):407–410.

    Article  PubMed  CAS  Google Scholar 

  41. Hui DS, Wong TY, Li TS, Ko FW, Choy DK, Szeto CC, et al. Prevalence of sleep disturbances in Chinese patients with end stage renal failure on maintenance hemodialysis. Med Sci Monit 2002; 8(5):CR331–CR336.

    PubMed  Google Scholar 

  42. Kuhlmann U, Becker HF, Birkhahn M, Peter JH, von Wichert P, Schutterle S, et al. Sleep-apnea in patients with end-stage renal disease and objective results. Clin Nephrol 2000; 53(6):460–466.

    PubMed  CAS  Google Scholar 

  43. Hui DS, Wong TY, Ko FW, Li TS, Choy DK, Wong KK, et al. Prevalence of sleep disturbances in Chinese patients with end-stage renal failure on continuous ambulatory peritoneal dialysis. Am J Kidney Dis 2000; 36(4):783–788.

    PubMed  CAS  Google Scholar 

  44. Wadhwa NK, Seliger M, Greenberg HE, Bergofsky E, Mendelson WB. Sleep related respiratory disorders in end-stage renal disease patients on peritoneal dialysis. Perit Dial Int 1992; 12(1):51–56.

    PubMed  CAS  Google Scholar 

  45. Wadhwa NK, Mendelson WB. A comparison of sleep-disordered respiration in ESRD patients receiving hemodialysis and peritoneal dialysis. Adv Perit Dial 1992; 8:195–198.

    PubMed  CAS  Google Scholar 

  46. Kutner NG, Bliwise DL, Brogan D, Zhang R. Race and restless sleep complaint in older chronic dialysis patients and nondialysis community controls. J Gerontol B Psychol Sci Soc Sci 2001; 56(3):170–175.

    Google Scholar 

  47. Puntriano M. The relationship between dialysis adequacies and sleep problems in hemodialysis patients. ANNA J 1999; 26(4):405–407.

    PubMed  CAS  Google Scholar 

  48. Evans RW, Rader B, Manninen DL. The quality of life of hemodialysis recipients treated with recombinant human erythropoietin. Cooperative Multicenter EPO Clinical Trial Group. JAMA 1990; 263(6):825–830.

    Article  PubMed  CAS  Google Scholar 

  49. Benz RL, Pressman MR, Hovick ET, Peterson DD. Potential novel predictors of mortality in end-stage renal disease patients with sleep disorders. Am J Kidney Dis 2000; 35(6):1052–1060.

    PubMed  CAS  Google Scholar 

  50. Virga G, Stanic L, Mastrosimone S, Gastaldon F, da Porto A, Bonadonna A. Hypercalcemia and insomnia in hemodialysis patients. Nephron 2000; 85(1):94–95.

    Article  PubMed  CAS  Google Scholar 

  51. Mendelson WB, Wadhwa NK, Greenberg HE, Gujavarty K, Bergofsky E. Effects of hemodialysis on sleep apnea syndrome in end-stage renal disease. Clin Nephrol 1990; 33(5): 247–251.

    PubMed  CAS  Google Scholar 

  52. Hallett MD, Burden S, Stewart D, Mahony J, Farrell PC. Sleep apnea in ESRD patients on HD and CAPD. Perit Dial Int 1996; 16 Suppl 1:S429–S433.

    PubMed  Google Scholar 

  53. Jean G, Piperno D, Francois B, Charra B. Sleep apnea incidence in maintenance hemodialysis patients: influence of dialysate buffer. Nephron 1995; 71(2):138–142.

    PubMed  CAS  Google Scholar 

  54. Parker KP, Bliwise DL, Bailey JL, Rye DB. Polysomnographic measures of nocturnal sleep in patients on chronic, intermittent daytime haemodialysis vs those with chronic kidney disease. Nephrol Dial Transpl 2005; 20(7):1422–1428.

    Article  Google Scholar 

  55. Guilleminault C, Abad VC. Obstructive sleep apnea syndromes. Med Clin North Am 2004; 88(3):611–30, viii.

    Article  PubMed  Google Scholar 

  56. Malhotra A, White DP. Obstructive sleep apnoea. Lancet 2002; 360(9328):237–245.

    Article  PubMed  Google Scholar 

  57. Strollo PJ, Jr., Rogers RM. Obstructive sleep apnea. N Engl J Med 1996; 334(2):99–104.

    Article  PubMed  Google Scholar 

  58. Gould GA, Whyte KF, Rhind GB, Airlie MA, Catterall JR, Shapiro CM, et al. The sleep hypopnea syndrome. Am Rev Respir Dis 1988; 137(4):895–898.

    PubMed  CAS  Google Scholar 

  59. Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 1993; 328(17):1230–1235.

    Article  PubMed  CAS  Google Scholar 

  60. Kimmel PL, Miller G, Mendelson WB. Sleep apnea syndrome in chronic renal disease. Am J Med 1989; 86(3):308–314.

    Article  PubMed  CAS  Google Scholar 

  61. Stepanski E, Faber M, Zorick F, Basner R, Roth T. Sleep disorders in patients on continuous ambulatory peritoneal dialysis. J Am Soc Nephrol 1995; 6(2):192–197.

    PubMed  CAS  Google Scholar 

  62. Shayamsunder AK, Patel SS, Jain V, Peterson RA, Kimmel PL. Sleepiness, sleeplessness, and pain in end-stage renal disease: distressing symptoms for patients. Semin Dial 2005; 18(2):109–118.

    Article  PubMed  Google Scholar 

  63. Fein AM, Niederman MS, Imbriano L, Rosen H. Reversal of sleep apnea in uremia by dialysis. Arch Intern Med 1987; 147(7):1355–1356.

    Article  PubMed  CAS  Google Scholar 

  64. Parker KP, Bliwise DL. Clinical comparison of hemodialysis and sleep apnea patients with excessive daytime sleepiness. ANNA J 1997; 24(6):663–665.

    PubMed  CAS  Google Scholar 

  65. Hanly P. Sleep apnea and daytime sleepiness in end-stage renal disease. Semin Dial 2004; 17(2):109–114.

    Article  PubMed  Google Scholar 

  66. Hanly PJ, Pierratos A. Improvement of sleep apnea in patients with chronic renal failure who undergo nocturnal hemodialysis. N Engl J Med 2001; 344(2):102–107.

    Article  PubMed  CAS  Google Scholar 

  67. Fletcher EC. Obstructive sleep apnea and the kidney. J Am Soc Nephrol 1993; 4(5):1111–1121.

    PubMed  CAS  Google Scholar 

  68. Sandblom RE, Matsumoto AM, Schoene RB, Lee KA, Giblin EC, Bremner WJ, et al. Obstructive sleep apnea syndrome induced by testosterone administration. N Engl J Med 1983; 308(9):508–510.

    Article  PubMed  CAS  Google Scholar 

  69. Perez RJ, Lipner H, Abdulla N, Cicotto S, Abrams M. Menstrual dysfunction of patients undergoing chronic hemodialysis. Obstet Gynecol 1978; 51(5):552–555.

    Article  PubMed  CAS  Google Scholar 

  70. Soreide E, Skeie B, Kirvela O, Lynn R, Ginsberg N, Manner T, et al. Branched-chain amino acid in chronic renal failure patients: respiratory and sleep effects. Kidney Int 1991; 40(3):539–543.

    Article  PubMed  CAS  Google Scholar 

  71. Sullivan CE, Issa FG, Berthon-Jones M, Eves L. Reversal of obstructive sleep apnoea by continuous positive airway pressure applied through the nares. Lancet 1981; 1(8225):862–865.

    Article  PubMed  CAS  Google Scholar 

  72. Pressman MR, Benz RL, Schleifer CR, Peterson DD. Sleep disordered breathing in ESRD: acute beneficial effects of treatment with nasal continuous positive airway pressure. Kidney Int 1993; 43(5):1134–1139.

    Article  PubMed  CAS  Google Scholar 

  73. Sanders MH, Gruendl CA, Rogers RM. Patient compliance with nasal CPAP therapy for sleep apnea. Chest 1986; 90(3):330–333.

    Article  PubMed  CAS  Google Scholar 

  74. Berry RB, Harding SM. Sleep and medical disorders. Med Clin North Am 2004; 88(3):679–703, ix.

    Article  PubMed  Google Scholar 

  75. Coleman RM, Pollak CP, Weitzman ED. Periodic movements in sleep (nocturnal myoclonus): relation to sleep disorders. Ann Neurol 1980; 8(4):416–421.

    Article  PubMed  CAS  Google Scholar 

  76. Rama AN, Kushida CA. Restless legs syndrome and periodic limb movement disorder. Med Clin North Am 2004; 88(3):653–667, viii.

    Article  PubMed  Google Scholar 

  77. Walters AS. Toward a better definition of the restless legs syndrome. The International Restless Legs Syndrome Study Group. Mov Disord 1995; 10(5):634–642.

    Article  PubMed  CAS  Google Scholar 

  78. Winkelman JW, Chertow GM, Lazarus JM. Restless legs syndrome in end-stage renal disease. Am J Kidney Dis 1996; 28(3):372–378.

    PubMed  CAS  Google Scholar 

  79. American Sleep Disorders Association. International Classification of Sleep Disorders. 1997. Rochester, MN.

    Google Scholar 

  80. Kavanagh D, Siddiqui S, Geddes CC. Restless legs syndrome in patients on dialysis. Am J Kidney Dis 2004; 43(5):763–771.

    Article  PubMed  Google Scholar 

  81. Benz RL, Pressman MR, Hovick ET, Peterson DD. A preliminary study of the effects of correction of anemia with recombinant human erythropoietin therapy on sleep, sleep disorders, and daytime sleepiness in hemodialysis patients (The SLEEPO study). Am J Kidney Dis 1999; 34(6):1089–1095.

    PubMed  CAS  Google Scholar 

  82. Wetter TC, Stiasny K, Kohnen R, Oertel WH, Trenkwalder C. Polysomnographic sleep measures in patients with uremic and idiopathic restless legs syndrome. Mov Disord 1998; 13(5):820–824.

    Article  PubMed  CAS  Google Scholar 

  83. Wetter TC, Trenkwalder C, Stiasny K, Pollmacher T, Kazenwadel J, Kohnen R, et al. Treatment of idiopathic and uremic restless legs syndrome with L-dopa–a double-blind cross-over study. Wien Med Wochenschr 1995; 145(17–18):525–527.

    PubMed  CAS  Google Scholar 

  84. Bhowmik D, Bhatia M, Tiwari S, Mahajan S, Gupta S, Agarwal SK et al. Low prevalence of restless legs syndrome in patients with advanced chronic renal failure in the Indian population: a case controlled study. Ren Fail 2004; 26(1):69–72.

    Article  PubMed  Google Scholar 

  85. Cirignotta F, Mondini S, Santoro A, Ferrari G, Gerardi R, Buzzi G. Reliability of a questionnaire screening restless legs syndrome in patients on chronic dialysis. Am J Kidney Dis 2002; 40(2):302–306.

    Article  PubMed  Google Scholar 

  86. Gigli GL, Adorati M, Dolso P, Piani A, Valente M, Brotini S et al. Restless legs syndrome in end-stage renal disease. Sleep Med 2004; 5(3):309–315.

    Article  PubMed  Google Scholar 

  87. Collado-Seidel V, Kohnen R, Samtleben W, Hillebrand GF, Oertel WH, Trenkwalder C. Clinical and biochemical findings in uremic patients with and without restless legs syndrome. Am J Kidney Dis 1998; 31(2):324–328.

    PubMed  CAS  Google Scholar 

  88. Ruottinen HM, Partinen M, Hublin C, Bergman J, Haaparanta M, Solin O, et al. An FDOPA PET study in patients with periodic limb movement disorder and restless legs syndrome. Neurology 2000; 54(2):502–504.

    PubMed  CAS  Google Scholar 

  89. Happe S, Klosch G, Saletu B, Zeitlhofer J. Treatment of idiopathic restless legs syndrome (RLS) with gabapentin. Neurology 2001; 57(9):1717–1719.

    PubMed  CAS  Google Scholar 

  90. Paulus W, Trenkwalder C. Less is more: pathophysiology of dopaminergic-therapy-related augmentation in restless legs syndrome. Lancet Neurol 2006; 5(10):878–886.

    Article  PubMed  CAS  Google Scholar 

  91. Earley CJ, Allen RP, Beard JL, Connor JR. Insight into the pathophysiology of restless legs syndrome. J Neurosci Res 2000; 62(5):623–628.

    Article  PubMed  CAS  Google Scholar 

  92. Silber MH. Restless legs syndrome. Mayo Clin Proc 1997; 72(3):261–264.

    Google Scholar 

  93. Sun ER, Chen CA, Ho G, Earley CJ, Allen RP. Iron and the restless legs syndrome. Sleep 1998; 21(4):371–377.

    PubMed  CAS  Google Scholar 

  94. Furst P. Amino acid metabolism in uremia. J Am Coll Nutr 1989; 8(4):310–323.

    PubMed  CAS  Google Scholar 

  95. Levine AS, Morley JE, Raij L. Opiates and the anorexia of uremia. Physiol Behav 1986; 37(6):835–838.

    Article  PubMed  CAS  Google Scholar 

  96. Montplaisir J, Nicolas A, Godbout R, Walters A. Restless legs syndrome and periodic limb movement disorder. In: Kryger MH, Roth T, Dement WC, eds. Principles and Practice of Sleep Medicine, 3rd edition. Philadelphia, PA: W.B. Saunders Company, 2000: 742–752.

    Google Scholar 

  97. Sloand JA, Shelly MA, Feigin A, Bernstein P, Monk RD. A double-blind, placebo-controlled trial of intravenous iron dextran therapy in patients with ESRD and restless legs syndrome. Am J Kidney Dis 2004; 43(4):663–670.

    Article  PubMed  CAS  Google Scholar 

  98. Winkelmann J, Stautner A, Samtleben W, Trenkwalder C. Long-term course of restless legs syndrome in dialysis patients after kidney transplantation. Mov Disord 2002; 17(5):1072–1076.

    Article  PubMed  Google Scholar 

  99. Walker SL, Fine A, Kryger MH. L-DOPA/carbidopa for nocturnal movement disorders in uremia. Sleep 1996; 19(3):214–218.

    PubMed  CAS  Google Scholar 

  100. Schreiner GE. Mental and personality changes in the uremic syndrome. Med Ann Dist Columbia 1959; 28(6):316–323.

    PubMed  CAS  Google Scholar 

  101. Parker KP, Bliwise DL, Bailey JL, Rye DB. Daytime sleepiness in stable hemodialysis patients. Am J Kidney Dis 2003; 41(2):394–402.

    Article  PubMed  Google Scholar 

  102. Adams N, Strauss M, Schluchter M, Redline S. Relation of measures of sleep-disordered breathing to neuropsychological functioning. Am J Respir Crit Care Med 2001; 163(7):1626–1631.

    PubMed  CAS  Google Scholar 

  103. Mendelson WB. Are periodic leg movements associated with clinical sleep disturbance? Sleep 1996; 19(3):219–223.

    PubMed  CAS  Google Scholar 

  104. Teschan PE, Bourne JR, Reed RB, Ward JW. Electrophysiological and neurobehavioral responses to therapy: The National Cooperative Dialysis Study. Kidney Int Suppl 1983;(13):S58–S65.

    Google Scholar 

  105. Balzer S, Kuttner K. Early auditory evoked potential. A diagnostic parameter in uremic encephalopathy. HNO 1996; 44(10):559–566.

    Article  PubMed  CAS  Google Scholar 

  106. Hamel B, Bourne JR, Ward JW, Teschan PE. Visually evoked cortical potentials in renal failure: transient potentials. Electroencephalogr Clin Neurophysiol 1978; 44(5):606–616.

    Article  PubMed  CAS  Google Scholar 

  107. Bro S, Olgaard K. Effects of excess PTH on nonclassical target organs. Am J Kidney Dis 1997; 30(5):606–620.

    PubMed  CAS  Google Scholar 

  108. Guisado R, Arieff AI, Massry SG, Lazarowitz V, Kerian A. Changes in the electroencephalogram in acute uremia. Effects of parathyroid hormone and brain electrolytes. J Clin Invest 1975; 55(4):738–745.

    Google Scholar 

  109. Goldstein DA, Feinstein EI, Chui LA, Pattabhiraman R, Massry SG. The relationship between the abnormalities in electroencephalogram and blood levels of parathyroid hormone in dialysis patients. J Clin Endocrinol Metab 1980; 51(1):130–134.

    Article  PubMed  CAS  Google Scholar 

  110. Ksiazek A. Brain serotonin and catecholamine turnover in uremic rats. Nephron 1982; 31(3):270–272.

    PubMed  CAS  Google Scholar 

  111. Schmid G, Bahner U, Peschkes J, Heidland A. Neurotransmitter and monoaminergic amino acid precursor levels in rat brain: effects of chronic renal failure and of malnutrition. Miner Electrolyte Metab 1996; 22(1–3):115–118.

    PubMed  CAS  Google Scholar 

  112. Iliescu EA, Coo H, McMurray MH, Meers CL, Quinn MM, Singer MA, et al. Quality of sleep and health-related quality of life in haemodialysis patients. Nephrol Dial Transplant 2003; 18(1):126–132.

    Article  PubMed  Google Scholar 

  113. Unruh ML, Levey AS, D’Ambrosio C, Fink NE, Powe NR, Meyer KB. Restless legs symptoms among incident dialysis patients: association with lower quality of life and shorter survival. Am J Kidney Dis 2004; 43(5):900–909.

    Article  PubMed  Google Scholar 

  114. Devins GM, Edworthy SM, Paul LC, Mandin H, Seland TP, Klein G, et al. Restless sleep, illness intrusiveness, and depressive symptoms in three chronic illness conditions: rheumatoid arthritis, end-stage renal disease, and multiple sclerosis. J Psychosom Res 1993; 37(2):163–170.

    Article  PubMed  CAS  Google Scholar 

  115. Mucsi I, Molnar MZ, Rethelyi J, Vamos E, Csepanyi G, Tompa G, et al. Sleep disorders and illness intrusiveness in patients on chronic dialysis. Nephrol Dial Transplant 2004; 19(7):1815–1822.

    Article  PubMed  Google Scholar 

  116. Sanner BM, Tepel M, Esser M, Klewer J, Hoehmann-Riese B, Zidek W, et al. Sleep-related breathing disorders impair quality of life in haemodialysis recipients. Nephrol Dial Transplant 2002; 17(7):1260–1265.

    Article  PubMed  Google Scholar 

  117. Shyamsunder A, Anekwe E, Khetpal P, Patel SS, Peterson R, Kimmel PL. Sleep distrubance, pain and quality of life in hemodialysis patients. Am Soc Nephrol 2003 (Abstract).

    Google Scholar 

  118. Patel SS, Cohen S, Khetpal P, Peterson RA, Kimmel PL. Comparison of pain, sleep disturbance, and quality of life parameters in CKD and general medicine outpatients. Am Soc Nephrol 2006 (Abstract).

    Google Scholar 

  119. Kurella M, Luan J, Lash JP, Chertow GM. Self-assessed sleep quality in chronic kidney disease. Int Urol Nephrol 2005; 37(1):159–165.

    Article  PubMed  Google Scholar 

  120. Lai KN, Lai KB, Lam CW, Chan TM, Li FK, Leung JC. Changes of cytokine profiles during peritonitis in patients on continuous ambulatory peritoneal dialysis. Am J Kidney Dis 2000; 35(4):644–652.

    PubMed  CAS  Google Scholar 

  121. Rousseau Y, Haeffner-Cavaillon N, Poignet JL, Meyrier A, Carreno MP. In vivo intracellular cytokine production by leukocytes during haemodialysis. Cytokine 2000; 12(5):506–517.

    Article  PubMed  CAS  Google Scholar 

  122. Plum F, Posner JB. Multifocal, diffuse, and metabolic brain diseases causing stupor or coma. In: Plum F, Posner JB, ed. The Diagnosis of Stupor and Coma. Philadelphia, F.A. Davis, 1985: 177–303.

    Google Scholar 

  123. Vaziri ND, Oveisi F, Reyes GA, Zhou XJ. Dysregulation of melatonin metabolism in chronic renal insufficiency: role of erythropoietin-deficiency anemia. Kidney Int 1996; 50(2):653–656.

    Article  PubMed  CAS  Google Scholar 

  124. Parker KP, Bliwise DL, Rye DB. Hemodialysis disrupts basic sleep regulatory mechanisms: buildi (125) Unruh M, Benz R, Greene T, Yan G, Beddhu S, DeVita M, et al. Effects of hemodialysis dose and membrane flux on health-related quality of life in the HEMO Study. Kidney Int 2004; 66(1):355–366.

    Google Scholar 

  125. Pierratos A, Ouwendyk M, Francoeur R, Vas S, Raj DS, Ecclestone AM, et al. Nocturnal hemodialysis: three-year experience. J Am Soc Nephrol 1998; 9(5):859–868.

    PubMed  CAS  Google Scholar 

  126. Hanly PJ, Gabor JY, Chan C, Pierratos A. Daytime sleepiness in patients with CRF: impact of nocturnal hemodialysis. Am J Kidney Dis 2003; 41(2):403–410.

    Article  PubMed  Google Scholar 

Download references

Authors
  1. Samir S. Patel
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Vivek Jain
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Paul L. Kimmel
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Section Psychopharmacology Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3508TB, PoBox 80082, Utrecht, The Netherlands

    Joris C. Verster

  2. Divison of Clinical Pharmacology and Experimental Therapeutics Department of Medicine, College of Physicians and Surgeons of Columbia University, 630 West 168th Street - Rm # BB813, New York, NY 10032, USA

    S. R. Pandi-Perumal

  3. Department of Psychiatry, Kunin-Lunenfeld Applied Research Unit (KLARU), 3560 Bathurst St., Toronto, M6A 2E1, Canada

    David L. Streiner

Rights and permissions

Reprints and permissions

Copyright information

© 2008 Humana Press, Totowa, NJ

About this chapter

Cite this chapter

Patel, S.S., Jain, V., Kimmel, P.L. (2008). Sleep and Quality of Life in Renal Disease. In: Verster, J.C., Pandi-Perumal, S.R., Streiner, D.L. (eds) Sleep and Quality of Life in Clinical Medicine. Humana Press. https://doi.org/10.1007/978-1-60327-343-5_41

Download citation

  • DOI: https://doi.org/10.1007/978-1-60327-343-5_41

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-60327-340-4

  • Online ISBN: 978-1-60327-343-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation